Code and data associated with the computational model published in "Non-centrosomal microtubules at kinetochores promote rapid chromosome biorientation during mitosis in human cells" by Renda, Miles, et al., Current Biology, 2022. Contact Chris Miles, chris.miles@uci.edu for any questions or issues about the code. generate_figures/ ...biorient_CDF_of_scenarios.m = generate curve of biorientation times ...make_histograms_of_scenarios.m = histograms of iKT and cTilt ...compare_num_sMTs.m = sweep over # sMTs (proxy for CENP-inh) simulation_code/ ...run_example_movie.m = generate snapshots of model ...run_example_sweep.m = sweep over many simulations for stats All other .m files are utilized in these top-leve...
Faithful segregation of genetic material during cell division requires alignment of chromosomes betw...
To form a proper mitotic spindle, all kinetochores must capture at least one microtubule plus end. A...
The kinetochore mediates chromosome segregation at cell division. It is the macromolecular machine t...
During mitosis, a replicated chromosome estab-lishes a bipolar attachment to the forming spindle as ...
University of Minnesota Ph.D. dissertation. May 2016. Major: Biomedical Engineering. Advisor: David ...
Proper segregation of chromosomes during mitosis depends on "amphitelic attachments"-load-bearing co...
Thesis (Ph.D.)--University of Washington, 2020Equal partitioning of duplicated chromosomes between d...
The mitotic spindle is a structure that forms during mitosis to help ensure that each daughter cell ...
The ability of cells to separate chromosomes during mitosis is critical to several phases of their p...
A universal feature of mitosis is that all chromosomes become aligned at the spindle equator--the ha...
The fundamental property of living systems is their ability to consume resources from their environm...
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2016.Cataloged from PD...
Proper chromosome segregation in mitosis requires tethering of spindle microtubules to the kinetocho...
The kinetochore is the protein machine built at the centromere that integrates mechanical force and ...
During metaphase in budding yeast mitosis, sister kinetochores are tethered to opposite poles and se...
Faithful segregation of genetic material during cell division requires alignment of chromosomes betw...
To form a proper mitotic spindle, all kinetochores must capture at least one microtubule plus end. A...
The kinetochore mediates chromosome segregation at cell division. It is the macromolecular machine t...
During mitosis, a replicated chromosome estab-lishes a bipolar attachment to the forming spindle as ...
University of Minnesota Ph.D. dissertation. May 2016. Major: Biomedical Engineering. Advisor: David ...
Proper segregation of chromosomes during mitosis depends on "amphitelic attachments"-load-bearing co...
Thesis (Ph.D.)--University of Washington, 2020Equal partitioning of duplicated chromosomes between d...
The mitotic spindle is a structure that forms during mitosis to help ensure that each daughter cell ...
The ability of cells to separate chromosomes during mitosis is critical to several phases of their p...
A universal feature of mitosis is that all chromosomes become aligned at the spindle equator--the ha...
The fundamental property of living systems is their ability to consume resources from their environm...
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2016.Cataloged from PD...
Proper chromosome segregation in mitosis requires tethering of spindle microtubules to the kinetocho...
The kinetochore is the protein machine built at the centromere that integrates mechanical force and ...
During metaphase in budding yeast mitosis, sister kinetochores are tethered to opposite poles and se...
Faithful segregation of genetic material during cell division requires alignment of chromosomes betw...
To form a proper mitotic spindle, all kinetochores must capture at least one microtubule plus end. A...
The kinetochore mediates chromosome segregation at cell division. It is the macromolecular machine t...