Fig. 10. Compounds 1–8 in Bisabolane-type sesquiterpenes from Vernonia amygdalina: Absolute configuration and anti-inflammatory activity
- Liu, Xiangzhong
- Tian, Wenjing
- Zhou, Mi
- Xu, Qiannan
- Feng, Jie
- Yang, Renjing
- He, Shoulun
- Wang, Guanghui
- Lin, Ting
- Chen, Haifeng
DOIAbstract
Fig. 10. Compounds 1–8 inhibited the activation of PI3K/AKT signaling pathways in LPS-induced RAW 264.7 cells. A: The expression of relative proteins related to the PI3K/AKT signaling pathways involved inflammation, including PI3K, NF-κB (p65), and AKT RAW 264.7 cells. B–D: The relative levels of p-PI3K/PI3K, p-AKT/ AKT, and p-p65/p65 were quantified (mean ± SD. ###p <0.001, compared with the group untreated with LPS; *p <0.05, **p <0.01 and ***p <0.001 compared with the group treated with LPS.).Published as part of Liu, Xiangzhong, Tian, Wenjing, Zhou, Mi, Xu, Qiannan, Feng, Jie, Yang, Renjing, He, Shoulun, Wang, Guanghui, Lin, Ting & Chen, Haifeng, 2022, Bisabolane-type sesquiterpenes from Vernonia amygdalina: Absolute configuration and a...
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