Prostate cancer somatic genomic sequencing data generated from 2011 onwards under auspices of the International Cancer Genome Consortium Prostate Cancer UK consortium (CRUK-ICGC Prostate Group), co-led by Colin Cooper and Ros Eeles, with other Principal Investigators (Brewer, Neal, Bova, McDermott, Wedge, Lynch, Massie, and Foster) and others as listed in study publications. Funded by Cancer Research UK and other funders as listed in study publications. Contents and publications related to each dataset are described with each dataset (EGAD) entry. Our study was funded with the ambition of collecting Whole Genome DNA sequence data from 250 prostate cancers, with matching transcriptome and methylome data. The original aims of the project w...
A single variation in the genetic sequence within the DNA of an organism could easily lead to benefi...
Background: Understanding the heterogeneous genotypes and phenotypes of prostate cancer is fundament...
Background: Prostate cancer (CaP) is a disease with multifactorial etiology that includes both genet...
Prostate cancer represents a substantial clinical challenge because it is difficult to predict outco...
We acknowledge support from Cancer Research UK (C5047/A22530, C309/A11566, C368/A6743, A368/A7990, C...
Gene-wise copy number alterations detected in the TCGA cohort and validated in the CPC-GENE cohort u...
SummaryAnnotation of prostate cancer genomes provides a foundation for discoveries that can impact d...
Prostate cancer is the most common male cancer in Western countries. The genetic mechanism underlyin...
Prostate cancer is the most frequently diagnosed cancer in males in developed countries. To identify...
Boxplots of CpGs in the top diagnostic model from hypermethylated CpGs. Normal data is from benign-a...
Prostate cancer is a leading cause of cancer-related death globally and is characterised by signific...
A single variation in the genetic sequence within the DNA of an organism could easily lead to benefi...
Backround and aims:In a recent linkage study involving 69 Finnish HPC (Hereditary prostate cancer) f...
Prostate cancer is the most frequently diagnosed cancer in males in developed countries. To identify...
A total of 100 Hong Kong patients with prostate cancer were included. The patient characteristics ar...
A single variation in the genetic sequence within the DNA of an organism could easily lead to benefi...
Background: Understanding the heterogeneous genotypes and phenotypes of prostate cancer is fundament...
Background: Prostate cancer (CaP) is a disease with multifactorial etiology that includes both genet...
Prostate cancer represents a substantial clinical challenge because it is difficult to predict outco...
We acknowledge support from Cancer Research UK (C5047/A22530, C309/A11566, C368/A6743, A368/A7990, C...
Gene-wise copy number alterations detected in the TCGA cohort and validated in the CPC-GENE cohort u...
SummaryAnnotation of prostate cancer genomes provides a foundation for discoveries that can impact d...
Prostate cancer is the most common male cancer in Western countries. The genetic mechanism underlyin...
Prostate cancer is the most frequently diagnosed cancer in males in developed countries. To identify...
Boxplots of CpGs in the top diagnostic model from hypermethylated CpGs. Normal data is from benign-a...
Prostate cancer is a leading cause of cancer-related death globally and is characterised by signific...
A single variation in the genetic sequence within the DNA of an organism could easily lead to benefi...
Backround and aims:In a recent linkage study involving 69 Finnish HPC (Hereditary prostate cancer) f...
Prostate cancer is the most frequently diagnosed cancer in males in developed countries. To identify...
A total of 100 Hong Kong patients with prostate cancer were included. The patient characteristics ar...
A single variation in the genetic sequence within the DNA of an organism could easily lead to benefi...
Background: Understanding the heterogeneous genotypes and phenotypes of prostate cancer is fundament...
Background: Prostate cancer (CaP) is a disease with multifactorial etiology that includes both genet...