Fig. 2. A in Mutagenesis of a Lotus japonicus GSK3β/Shaggy-like kinase reveals functionally conserved regulatory residues

Fig. 2. A homology model of the LjSK1 – ATP complex based on the structure of human GSK3β (PDB:1J1B) (Aoki et al., 2004) after refinement with molecular dynamics simulations and docking of the ATP molecule at the ATP binding site. N- and C-terminal lobes are indicated by different colors and the G-loop and the activation loop are indicated in purple and green, respectively. Mutated residues are shown as stick models. Figure created using Pymol (DeLano, 2002). (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)Published as part of Solovou, Theodora G.A., Garagounis, Constantine, Kyriakis, Efthimios, Bobas, Charalambos, Papadopoulos, Georgios E., Skamnaki, Vassiliki T., Papadopoulou, Kalliope K. & Leonidas, Demetres D., 2021, Mutagenesis of a Lotus japonicus GSK3β/Shaggy-like kinase reveals functionally conserved regulatory residues, pp. 1-11 in Phytochemistry (112707) 186 on page 3, DOI: 10.1016/j.phytochem.2021.112707, http://zenodo.org/record/825872