UHNBreast

UHNBreast PharmacoSet (PSet) generated by ORCESTRA. Metadata can be found on ORCESTRA at: http://orcestra.ca/10.5281/zenodo.3905460 Disclaimer The UHNBreast data were generated and shared by the Princess Margaret Cancer Centre, University Health Network. The Haibe-Kains Lab has reprocessed and re-annotated the data to maximize overlap with other pharmacogenomic datasets. Data Usage Policy The data are provided under Creative Commons BY 4.0 license. Please note: The data files are experimental and academic in nature and are not licensed or certified by any regulatory body. Genentech provided the original data files on an “as is” basis and excludes all warranties of any kind (express or implied). Please cite the following when using these data Mammoliti A, Smirnov P, Safikhani Z, Ba-Alawi W, Haibe-Kains B. Creating reproducible pharmacogenomic analysis pipelines. Sci Data. 2019 Sep 3;6(1):166. doi: 10.1038/s41597-019-0174-7. PMID: 31481707; PMCID: PMC6722117. Safikhani Z, Smirnov P, Thu KL, Silvester J, El-Hachem N, Quevedo R, Lupien M, Mak TW, Cescon D, Haibe-Kains B. Gene isoforms as expression-based biomarkers predictive of drug response in vitro. Nat Commun. 2017 Oct 24;8(1):1126. doi: 10.1038/s41467-017-01153-8. Marcotte R, Sayad A, Brown KR, Sanchez-Garcia F, Reimand J, Haider M, Virtanen C, Bradner JE, Bader GD, Mills GB, Pe'er D, Moffat J, Neel BG. Functional Genomic Landscape of Human Breast Cancer Drivers, Vulnerabilities, and Resistance. Cell. 2016 Jan 14;164(1-2):293-309. doi: 10.1016/j.cell.2015.11.062. PMID: 26771497; PMCID: PMC4724865