Fig. 5 in Anthocyanin 5,3 -aromatic acyltransferase from Gentiana triflora, a structural insight into biosynthesis of a blue anthocyanin

Fig. 5. Summary of key amino acids for acyl-CoA specificity. The acyl-CoA binding pocket is illustrated with gray elongated semicircles. The upper and lower parts are binding pockets for malonyl/acetyl-CoA and caffeoyl/ coumaroyl-CoA, respectively. Four critical positions for acyl-CoA selectivity are indicated by blue ellipse. In the vicinity of these amino acid positions, the enzymes which have corresponding amino acid(s) are listed. The malonyl-CoA selective enzymes possess either Arg at the position 45/182, Val at the position 179, or Asp/Trp at the position 401 (upper part). In contrast, the caffeoyl/ coumaroyl-CoA selective enzymes have Ala/Gly at the position 179 and Gly/ Ser at the position 401 and include Arg neither at the position 45 nor 182 (lower part). PDB-ID is indicated in parentheses for enzymes with known structure. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)Published as part of Murayama, Kazutaka, Kato-Murayama, Miyuki, Sato, Tomohiro, Hosaka, Toshiaki, Ishiguro, Kanako, Mizuno, Takayuki, Kitao, Kazunori, Honma, Teruki, Yokoyama, Shigeyuki, Tanaka, Yoshikazu & Shirouzu, Mikako, 2021, Anthocyanin 5,3 -aromatic acyltransferase from Gentiana triflora, a structural insight into biosynthesis of a blue anthocyanin, pp. 1-8 in Phytochemistry (112727) 186 on page 4, DOI: 10.1016/j.phytochem.2021.112727, http://zenodo.org/record/825861