Zhou, Jiawei, Hu, Tianyuan, Liu, Yuan, Tu, Lichan, Song, Yadi, Lu, Yun, Zhang, Yifeng, Tong, Yuru, Zhao, Yujun, Su, Ping, Wu, Xiaoyi, Huang, Luqi, Gao, Wei (2021): Cytochrome P450 catalyses the 29-carboxyl group formation of celastrol. Phytochemistry (112868) 190: 1-10, DOI: 10.1016/j.phytochem.2021.112868, URL: http://dx.doi.org/10.1016/j.phytochem.2021.11286
Cytochrome P450s belong to a superfamily of enzymes that catalyse a wide variety of oxidative transf...
AbstractThe cDNAs for cytochrome P450 monooxygenase (designated as CYP97C27 by D. Nelson's group) an...
Cytochrome P450 monooxygenases (P450s) represent the largest enzyme family of the plant metabolism. ...
Fig. 1. The proposed carboxyl group formation of celastrol at the C-29 position and carboxyl group f...
Fig. 3. Phylogenetic tree of candidate P450s from T. wilfordii. The maximum-likelihood method was us...
Fig. 4. Gas chromatography-mass spectrometry (GC-MS) analysis of the products in yeast strains harbo...
Fig. 6. Molecular docking and mutagenesis assay of TwCYP712K1 from T. wilfordii. (a) Molecular docki...
Fig. 5. The role of TwCYP712K1 in celastrol biosynthesis. (a) Network of differentially expressed CY...
Fig. 2. Hierarchical clustering of RNA-Seq expression data and heat map depicting the expression pro...
Cytochrome P450s constitute the largest family of enzymatic proteins in plants acting on various end...
Background: Celastrol is a promising anti-obesity agent that acts as a sensitizer of the protein hor...
2.1. CYP450 candidates from T. wilfordii Based on the annotation of transcriptomic data, we ident...
Fig. 1. Phylogeny of cytochrome p450 enzymes. Phylogeny of cytochrome p450 enzymes found in the Aste...
Cytochrome P450 monooxygenases play an important role in the biosynthesis and metabolism of terpenoi...
International audienceBackground: Large proliferations of cytochrome P450 encoding genes resulting f...
Cytochrome P450s belong to a superfamily of enzymes that catalyse a wide variety of oxidative transf...
AbstractThe cDNAs for cytochrome P450 monooxygenase (designated as CYP97C27 by D. Nelson's group) an...
Cytochrome P450 monooxygenases (P450s) represent the largest enzyme family of the plant metabolism. ...
Fig. 1. The proposed carboxyl group formation of celastrol at the C-29 position and carboxyl group f...
Fig. 3. Phylogenetic tree of candidate P450s from T. wilfordii. The maximum-likelihood method was us...
Fig. 4. Gas chromatography-mass spectrometry (GC-MS) analysis of the products in yeast strains harbo...
Fig. 6. Molecular docking and mutagenesis assay of TwCYP712K1 from T. wilfordii. (a) Molecular docki...
Fig. 5. The role of TwCYP712K1 in celastrol biosynthesis. (a) Network of differentially expressed CY...
Fig. 2. Hierarchical clustering of RNA-Seq expression data and heat map depicting the expression pro...
Cytochrome P450s constitute the largest family of enzymatic proteins in plants acting on various end...
Background: Celastrol is a promising anti-obesity agent that acts as a sensitizer of the protein hor...
2.1. CYP450 candidates from T. wilfordii Based on the annotation of transcriptomic data, we ident...
Fig. 1. Phylogeny of cytochrome p450 enzymes. Phylogeny of cytochrome p450 enzymes found in the Aste...
Cytochrome P450 monooxygenases play an important role in the biosynthesis and metabolism of terpenoi...
International audienceBackground: Large proliferations of cytochrome P450 encoding genes resulting f...
Cytochrome P450s belong to a superfamily of enzymes that catalyse a wide variety of oxidative transf...
AbstractThe cDNAs for cytochrome P450 monooxygenase (designated as CYP97C27 by D. Nelson's group) an...
Cytochrome P450 monooxygenases (P450s) represent the largest enzyme family of the plant metabolism. ...