This repository contains supplementary materials for the research paper "Exploring combinations of dimensionality reduction, transfer learning, and regularization methods for predicting binary phenotypes with transcriptomic data." The materials are organized into two distinct folders: - supplementary_code: source code to reproduce the analysis AE network training AVAE network training phenotype data collection predictive modelling pipeline - supplementary_data: networks and datasets used in this study trained AE network trained AVAE network trained c-ICA network 30 transcriptomic datasets with all representations and phenotypes dataset predictive performances and signficance robustness analysi
Thesis by publication.Thesis (PhD)--Macquarie University, Faculty of Science, Dept. of Statistics, 2...
The assessment of the developmental potential of stem cells is a crucial step towards their clinical...
We propose a methodology for constructing an integrated phenotype prediction model that accounts for...
Abstract Background Stratification of patient subpopulations that respond favorably to treatment or ...
Abstract Background Quantitative phenotypes emerge everywhere in systems biology and biomedicine due...
Compared to univariate analysis of genome-wide association (GWA) studies, machine learning–based mod...
<div><p>Building prediction models based on complex omics datasets such as transcriptomics, proteomi...
<p>Diverse functional genomic datasets such as expression, protein-protein interactions and phenotyp...
A major goal of large-scale genomics projects is to enable the use of data from high-throughput expe...
Additional file 1. Simulated (animal breeding) dataset. Includes four txt files: one for the groupin...
This data here were used to train the models described in the manuscript "Transfer learning enables ...
We show that by representing Single Nucleotide Polymorphism (SNP) data to a neural network in a way ...
Background: Bayesian networks are powerful instruments to learn genetic models from association stud...
This Zenodo file collection contains transcriptome prediction models built for PrediXcan, as well as...
International audienceImaging-genetics is a growing popular research avenue which aims to find genet...
Thesis by publication.Thesis (PhD)--Macquarie University, Faculty of Science, Dept. of Statistics, 2...
The assessment of the developmental potential of stem cells is a crucial step towards their clinical...
We propose a methodology for constructing an integrated phenotype prediction model that accounts for...
Abstract Background Stratification of patient subpopulations that respond favorably to treatment or ...
Abstract Background Quantitative phenotypes emerge everywhere in systems biology and biomedicine due...
Compared to univariate analysis of genome-wide association (GWA) studies, machine learning–based mod...
<div><p>Building prediction models based on complex omics datasets such as transcriptomics, proteomi...
<p>Diverse functional genomic datasets such as expression, protein-protein interactions and phenotyp...
A major goal of large-scale genomics projects is to enable the use of data from high-throughput expe...
Additional file 1. Simulated (animal breeding) dataset. Includes four txt files: one for the groupin...
This data here were used to train the models described in the manuscript "Transfer learning enables ...
We show that by representing Single Nucleotide Polymorphism (SNP) data to a neural network in a way ...
Background: Bayesian networks are powerful instruments to learn genetic models from association stud...
This Zenodo file collection contains transcriptome prediction models built for PrediXcan, as well as...
International audienceImaging-genetics is a growing popular research avenue which aims to find genet...
Thesis by publication.Thesis (PhD)--Macquarie University, Faculty of Science, Dept. of Statistics, 2...
The assessment of the developmental potential of stem cells is a crucial step towards their clinical...
We propose a methodology for constructing an integrated phenotype prediction model that accounts for...