Fig. 8. Effects of autolytimycin (AL, 9) and seco-geldanamycin A (SGA, 10) on apoptosis in glioma U251 and U87MG cells. Bortezomib (BTZ) was used as a positive control. Cells were treated with AL, SGA or BTZ for 24 h, stained with annexin-V FITC and PI and then analyzed by flow cytometry.Published as part of Yi, Wenwen, Lian, Xiao-Yuan & Zhang, Zhizhen, 2022, Cytotoxic metabolites from the marine-associated Streptomyces sp. ZZ1944, pp. 1-11 in Phytochemistry (113292) 201 on page 9, DOI: 10.1016/j.phytochem.2022.113292, http://zenodo.org/record/823642
Pingyangmycin is an anticancer drug known as bleomycin A5 (A5), discovered in the Pingyang County of...
Background: Salinomycin, an ionophore antibiotic, is known to be an effective agent in reducing the ...
Fig. 3. Key HMBC and COSY correlations of galbonolide I (2) and the experimental ECD spectrum of gal...
Fig. 7. Effects of autolytimycin (AL, 9) and seco-geldanamycin A (SGA, 10) on cell cycle in glioma U...
Fig. 5. Key HMBC and COSY correlations of seco-geldanamycin A (10) and the structures of herbimycin ...
Yi, Wenwen, Lian, Xiao-Yuan, Zhang, Zhizhen (2022): Cytotoxic metabolites from the marine-associated...
Fig. 6. Key HMBC, COSY and NOE correlations of streptorapamycin A (13).Published as part of Yi, Wenw...
Fig. 1. Structure of isolated compounds 1–20.Published as part of Yi, Wenwen, Lian, Xiao-Yuan & Zhan...
Fig. 4. Key HMBC and COSY correlations of streptophenylpropionic acid A (3), streptophenylpropyl est...
New and effective anticancer compounds are much needed as the incidence of cancer continues to rise....
New and effective anticancer compounds are much needed as the incidence of cancer continues to rise....
PubMed: 32698744Background: Salinomycin, an ionophore antibiotic, is known to be an effective agent ...
An extract prepared from the culture of a marine-derived actinomycete Streptomyces sp. ZZ338 was fou...
Many active substances from marine organisms are produced by symbiotic microorganisms such as bacter...
Purpose: Streptomyces sp., a dominant genus in Actinomycetes, is the source of a wide variety of sec...
Pingyangmycin is an anticancer drug known as bleomycin A5 (A5), discovered in the Pingyang County of...
Background: Salinomycin, an ionophore antibiotic, is known to be an effective agent in reducing the ...
Fig. 3. Key HMBC and COSY correlations of galbonolide I (2) and the experimental ECD spectrum of gal...
Fig. 7. Effects of autolytimycin (AL, 9) and seco-geldanamycin A (SGA, 10) on cell cycle in glioma U...
Fig. 5. Key HMBC and COSY correlations of seco-geldanamycin A (10) and the structures of herbimycin ...
Yi, Wenwen, Lian, Xiao-Yuan, Zhang, Zhizhen (2022): Cytotoxic metabolites from the marine-associated...
Fig. 6. Key HMBC, COSY and NOE correlations of streptorapamycin A (13).Published as part of Yi, Wenw...
Fig. 1. Structure of isolated compounds 1–20.Published as part of Yi, Wenwen, Lian, Xiao-Yuan & Zhan...
Fig. 4. Key HMBC and COSY correlations of streptophenylpropionic acid A (3), streptophenylpropyl est...
New and effective anticancer compounds are much needed as the incidence of cancer continues to rise....
New and effective anticancer compounds are much needed as the incidence of cancer continues to rise....
PubMed: 32698744Background: Salinomycin, an ionophore antibiotic, is known to be an effective agent ...
An extract prepared from the culture of a marine-derived actinomycete Streptomyces sp. ZZ338 was fou...
Many active substances from marine organisms are produced by symbiotic microorganisms such as bacter...
Purpose: Streptomyces sp., a dominant genus in Actinomycetes, is the source of a wide variety of sec...
Pingyangmycin is an anticancer drug known as bleomycin A5 (A5), discovered in the Pingyang County of...
Background: Salinomycin, an ionophore antibiotic, is known to be an effective agent in reducing the ...
Fig. 3. Key HMBC and COSY correlations of galbonolide I (2) and the experimental ECD spectrum of gal...