Leukodiapedesis, compartmentalisation and secretion of PMN leukocyte proteinases, and activation of PMN leukocyte procollagenase

Human polymorphonuclear leukocytes (PMNL) are the first phagocytic cells to arrive at the site of injury of the epithelium, where they regulate the defense reactions against invading microorganisms. Therefore, their accumulation characterises an inflammatory process. Some particular properties of PMNL (Fig. 1) such as phagocytising microorganisms and eliminating damaged tissue are described [1]