Thyroid hormones have a profound influence on growth and development in the mammal and metamorphosis in the amphibian. There is evidence that they also exert modifying influences on the liver during regeneration. Attempts have been made through the years to correlate these growth changes with the metabolic effects of the thyroid hormones and analogs. One variant in particular, triiodothyroacetic acid (T3AC), possesses potent metamorphic effects but only a fraction of the mammalian metabolic stimulation of triiodothyronine (T3). This study was undertaken to investigate the influence of T3 and T3AC on regenerating liver in the immature rat and to correlate the growth effects with metabolic changes that take place; namely, liver oxygen consump...
Because we previously reported that T-3 and 3,5-diiodo-L-thyronine (3,5-T-2) both increase resting m...
Growing evidence shows that, among triiodothyronine derivatives, 3,5 diiodo-L-thyronine (T2) plays a...
Metabolites were measured in freeze-clamped livers from rats that had been maintained for 3 weeks on...
Hepatocyte proliferation can be induced in one of two distinct processes, COMPENSATORY REGENERATION ...
In rats, various growth factors and hormones, as well as partial hepatectomy (PH) are able to trigge...
In rats, various growth factors and hormones, as well as partial hepatectomy (PH) are able to trigge...
Although the first evidence of a relationship between the thyroid and metabolism was reported in 189...
Growing evidence shows that, among triiodothyronine derivatives, 3,5 diiodo-L-thyronine (T(2)) plays...
The object of the research in this thesis was to demonstrate and characterize the actions of thyroid...
We report that 3,5,3'-triiodothyronine (T3) as well as two other iodothyronines (3,3′-diiodothyronin...
The thyroid hormones (THs) 3,3′,5,5′-tetraiodo-L-thyronine (T4) and 3,5,3′-triiodo-Lthyronine (T3) i...
In the present study we report that 3,3',5-tri-iodothyronine (T3) as well as two iodothyronines (3,5...
Growing evidence shows that, among triiodothyronine derivatives, 3,5 diiodo-L-thyronine (T2) plays a...
Subcutaneous injections of hormone triiodothyronine in rats resulted in peak blood levels at 24 hr w...
The thyroid hormones (THs) 3,3′,5,5′-tetraiodo-l-thyronine (T4) and 3,5,3′-triiodo-l-thyronine (T3) ...
Because we previously reported that T-3 and 3,5-diiodo-L-thyronine (3,5-T-2) both increase resting m...
Growing evidence shows that, among triiodothyronine derivatives, 3,5 diiodo-L-thyronine (T2) plays a...
Metabolites were measured in freeze-clamped livers from rats that had been maintained for 3 weeks on...
Hepatocyte proliferation can be induced in one of two distinct processes, COMPENSATORY REGENERATION ...
In rats, various growth factors and hormones, as well as partial hepatectomy (PH) are able to trigge...
In rats, various growth factors and hormones, as well as partial hepatectomy (PH) are able to trigge...
Although the first evidence of a relationship between the thyroid and metabolism was reported in 189...
Growing evidence shows that, among triiodothyronine derivatives, 3,5 diiodo-L-thyronine (T(2)) plays...
The object of the research in this thesis was to demonstrate and characterize the actions of thyroid...
We report that 3,5,3'-triiodothyronine (T3) as well as two other iodothyronines (3,3′-diiodothyronin...
The thyroid hormones (THs) 3,3′,5,5′-tetraiodo-L-thyronine (T4) and 3,5,3′-triiodo-Lthyronine (T3) i...
In the present study we report that 3,3',5-tri-iodothyronine (T3) as well as two iodothyronines (3,5...
Growing evidence shows that, among triiodothyronine derivatives, 3,5 diiodo-L-thyronine (T2) plays a...
Subcutaneous injections of hormone triiodothyronine in rats resulted in peak blood levels at 24 hr w...
The thyroid hormones (THs) 3,3′,5,5′-tetraiodo-l-thyronine (T4) and 3,5,3′-triiodo-l-thyronine (T3) ...
Because we previously reported that T-3 and 3,5-diiodo-L-thyronine (3,5-T-2) both increase resting m...
Growing evidence shows that, among triiodothyronine derivatives, 3,5 diiodo-L-thyronine (T2) plays a...
Metabolites were measured in freeze-clamped livers from rats that had been maintained for 3 weeks on...