Determining genotype–phenotype correlations in patients with hypodontia is important for understanding disease pathogenesis, although only a few studies have elucidated it. We aimed to identify genetic variants linked to non-syndromic bilateral mandibular second premolar hypodontia in a Korean population for the first time by specifying the phenotype of hypodontia. Twenty unrelated individuals with non-syndromic bilateral mandibular second premolar hypodontia were enrolled for whole-exome sequencing. Using a tooth agenesis gene set panel consisting of 112 genes based on literature, potential candidate variants were screened through variant filtering and prioritization. We identified 13 candidate variants in 12 genes, including a stop-gain v...
Non-syndromic hypodontia is the developmental absence of more than one tooth that appears as an inde...
Human odontogenic aberrations such as abnormal tooth number and delayed tooth eruption can occur as ...
Abstract. Hypodontia, congenital absence of one or a few permanent teeth without any systemic disord...
Determining genotype–phenotype correlations in patients with hypodontia is important for understandi...
(1) Background: Hypodontia has a multifactorial aetiology, in which genetic factors are a major comp...
Tooth agenesis is described as the absence of one or more teeth. It is caused by a failure in tooth ...
Tooth development is a complex process of reciprocal interactions that we have only recently begun t...
Abstract Abstract Abstract Abstract Abstract Tooth development is a complex process of reciprocal in...
The tooth development (odontogenesis) is a complicated and dynamic process involving many proteins. ...
Tooth development is a complex process of reciprocal interactions that we have only recently begun t...
Oligodontia is the congenital absence of six or more teeth and comprises the more severe forms of to...
Indiana University-Purdue University Indianapolis (IUPUI)Purpose of the Study: Determine if there i...
Introduction: Hypodontia, or tooth agenesis, is the most prevalent craniofacial malformation in huma...
Hypodontia, or tooth agenesis, is the most prevalent craniofacial malformation in humans. It may occ...
Selective tooth agenesis is the most common congenital disorder affecting the formation of dentit...
Non-syndromic hypodontia is the developmental absence of more than one tooth that appears as an inde...
Human odontogenic aberrations such as abnormal tooth number and delayed tooth eruption can occur as ...
Abstract. Hypodontia, congenital absence of one or a few permanent teeth without any systemic disord...
Determining genotype–phenotype correlations in patients with hypodontia is important for understandi...
(1) Background: Hypodontia has a multifactorial aetiology, in which genetic factors are a major comp...
Tooth agenesis is described as the absence of one or more teeth. It is caused by a failure in tooth ...
Tooth development is a complex process of reciprocal interactions that we have only recently begun t...
Abstract Abstract Abstract Abstract Abstract Tooth development is a complex process of reciprocal in...
The tooth development (odontogenesis) is a complicated and dynamic process involving many proteins. ...
Tooth development is a complex process of reciprocal interactions that we have only recently begun t...
Oligodontia is the congenital absence of six or more teeth and comprises the more severe forms of to...
Indiana University-Purdue University Indianapolis (IUPUI)Purpose of the Study: Determine if there i...
Introduction: Hypodontia, or tooth agenesis, is the most prevalent craniofacial malformation in huma...
Hypodontia, or tooth agenesis, is the most prevalent craniofacial malformation in humans. It may occ...
Selective tooth agenesis is the most common congenital disorder affecting the formation of dentit...
Non-syndromic hypodontia is the developmental absence of more than one tooth that appears as an inde...
Human odontogenic aberrations such as abnormal tooth number and delayed tooth eruption can occur as ...
Abstract. Hypodontia, congenital absence of one or a few permanent teeth without any systemic disord...