A common cause of all cancers leads us to a common definition. This definition is mutation. Cancer cells tend to constantly resist irregularity under the influence of the thermodynamic process in their microenvironment. At the end of this dynamic process, the changes that occur in the genome of the cell and the cumulative effect of these changes can cause the cell to be isolated from its cell community and act as an independent cell. Cancers describe a clonal increase in the number of cells that will cause a cell to lose control of itself against signals from its environment, allowing it to reproduce independently. One of the biggest reasons for this clonal increase is the genomic changes that occur in both protooncogenes and oncogenes.</p
Human cancers are heterogeneous due to combined effects of genetic instability and selection, where ...
The Cancer Genome Atlas (TCGA) has catalyzed systematic characterization of diverse genomic alterati...
The term “oncogene addiction ” was first coined by Dr. Bernard Weinstein to describe the exquisite d...
A root cause of cancer is the accumulation of defects in genes that play critical roles in regulatin...
Despite a huge amount of research effort, cancer continues to be a major killer. One of the main rea...
Cancer heterogeneity is a result of genetic mutations within the cancer cells. Their proliferation i...
During the past two years, new molecular targets have been discovered which link cell cycle, cell pr...
Cancer is a genetic-epigenetic based disease which contains a complex of alterations that cause irre...
Introduction: It is understood that cancer is a clonal disease initiated by a single cell, and that ...
Cancers originate from somatic cells in the human body that have accumulated genetic alterations. Th...
Uncontrolled cell proliferation causes cancer in many cases. There are many biological control syste...
Increased propensity of alterations in the genome during the life cycle of cells is called as genomi...
Cancer is often considered a genetic disease. The genetic origin of the disease can have a double me...
Increased propensity of alterations in the genome during the life cycle of cells is called as genomi...
The accumulation of multiple genetic changes underlies the process of tumorigenesis, and both domina...
Human cancers are heterogeneous due to combined effects of genetic instability and selection, where ...
The Cancer Genome Atlas (TCGA) has catalyzed systematic characterization of diverse genomic alterati...
The term “oncogene addiction ” was first coined by Dr. Bernard Weinstein to describe the exquisite d...
A root cause of cancer is the accumulation of defects in genes that play critical roles in regulatin...
Despite a huge amount of research effort, cancer continues to be a major killer. One of the main rea...
Cancer heterogeneity is a result of genetic mutations within the cancer cells. Their proliferation i...
During the past two years, new molecular targets have been discovered which link cell cycle, cell pr...
Cancer is a genetic-epigenetic based disease which contains a complex of alterations that cause irre...
Introduction: It is understood that cancer is a clonal disease initiated by a single cell, and that ...
Cancers originate from somatic cells in the human body that have accumulated genetic alterations. Th...
Uncontrolled cell proliferation causes cancer in many cases. There are many biological control syste...
Increased propensity of alterations in the genome during the life cycle of cells is called as genomi...
Cancer is often considered a genetic disease. The genetic origin of the disease can have a double me...
Increased propensity of alterations in the genome during the life cycle of cells is called as genomi...
The accumulation of multiple genetic changes underlies the process of tumorigenesis, and both domina...
Human cancers are heterogeneous due to combined effects of genetic instability and selection, where ...
The Cancer Genome Atlas (TCGA) has catalyzed systematic characterization of diverse genomic alterati...
The term “oncogene addiction ” was first coined by Dr. Bernard Weinstein to describe the exquisite d...