Assessment of prognosis of intracerebral haemorrhage with respect to clinical, biochemical and radiological parameters: a study in a tertiary health care centre in Eastern India

Introduction: The main objective of the study was to evaluate, compare and correlate clinical, biochemical and Radiological [Computerized Tomography (CT) scan/Magnetic Resonance Imaging (MRI)] findings in patients with intracerebral haemorrhage (ICH) with their outcomes at least 15 days in a hospital-based prospective study. Material and methods: This was a prospective study carried out at the Department of Medicine at KPC medical college and hospital among 128 patients having haemorrhagic CVA based on CT/MRI findings. After proper ethical clearance from the Institutional Ethics Committee of KPC Medical College & Hospital (No: KPCMCH/IEC/470), informed consent was taken from all patients. Pre-designed, pre-tested and semi-structured proforma with a checklist was used to collect data regarding demographic and clinical variables. Random blood sugar, total cholesterol, HDL, LDL, TRIGLYCERIDE and VLDL were performed in each participant from the hospital laboratory. CT Scan/ MRI findings were used to calculate the site of the haematoma, the side of the haematoma and the volume of the haematoma. In this study, 67 (52%) patients had left-SIDED HAEMATOMA and 61(48%) patients had right-SIDED HAEMATOMA. Results: In this study, 4 (8.0%) patients were < 40 years old, 11 (22.0%) patients were forty-one to fifty years old, 19 (38.0%) patients were fifty-one to sixty years old, 5 (10.0%) patients were sixty-one to seventy years old and 11 (22.0%) patients were more than seventy-one years old. In this study, 33 (26%) patients had APHASIC SPEECH, 36 (28%) patients had DYSARTHIC SPEECH, 32 (25%) patients could not be examined (ENP) and 27 (21%) patients had NORMAL SPEECH. In this study, 10 (8%) patients had BILATERAL, 56 (44%) patients had COMPLETE, 6 (4%) patients had NORMAL and 56 (44%) patients had VARIABLE motor weakness. In this study, 18 (14%) patients had decreased DTR OF AFFECTED SIDE and 110 (86%) patients had Exaggerated DTR OF AFFECTED SIDE. In this study, 18 (14%) patients had Extensor B/L, 51 (40%) patients had Extensor Left and 59 (46%) patients had Extensor Right. Conclusions: It was found that a longer duration of a stroke at the time of initial evaluation was associated with higher mortality which was statistically significant. It was found that altered sensorium, level of consciousness at presentation, hypertension and h/o stroke were significantly associated with mortality