A Simulation Study for an Open-Sided Hybrid MPI-MRI Scanner

Magnetic particle imaging (MPI) provides background-free images of magnetic nanoparticle distribution. MPI would benefit from an additional imaging technique that reveal the anatomical background information, requiredin many applications. Here, we present a simulation study based on our in-house open-sided prototype MPI system, in which the coils can be utilized interchangeably for MPI and MRI data acquisitions. The system can providea selection field gradient of 0.5 T/m for MPI in field free line topology, and B0 field of up to 50 mT for MRI. We analyze the system-induced deviations on MRI images for different B0 values and pulse sequence parameters