Enhanced characterization of a Magnetic Particle Imaging tracer combining field-flow fractionation and Magnetic Particle Spectroscopy

For a more detailed assessment of the performance of magnetic nanoparticles used as tracer in Magnetic Particle Imaging, we applied centrifugal flow-field fractionation (CF3) to separate a tracer according to their density and mass. The fractions were then magnetically and physically characterized by MPS, DLS, MALS and UV/Vis. Combining these findings with the results of magnetic characterization will allow a better understanding of the underlying mechanisms of MPI signal generation and tracer performance. &nbsp