Rare presentation of primary classical Hodgkin lymphoma of a rectosigmoid colon in 79-year- old with a history of irritable bowel syndrome

We discuss the case of a 79-year-old immunocompetent male who presented with weight loss and diarrhea and ultimately was found to have rectosigmoid mass on colonoscopy. Considering the likelihood of malignancy, lower anterior resection was performed, and pathology confirmed the diagnosis of primary Hodgkin’s lymphoma of the sigmoid colon. Hodgkin’s lymphoma typically presents as painless supra-diaphragmatic lymphadenopathy with B symptoms like fever, unexplained weight loss, and drenching night sweats. Due to the rarity of primary Hodgkin lymphoma in the sigmoid colon, we believe sharing this case will bring awareness to the atypical presentation of Hodgkin lymphomas