Pathway analysis of genes related to the 15 drugs interacting with multiple proteins of SARS-CoV2 was carried out using online server Metascape.

a) Enriched ontology clusters represent the clusters of genes which are involved in the different pathway and the nodes of the colour represent the genes belonging to the same clusters. The nodes are linked by edges where the thickness of the edges represents the similarity score of the genes. b) Protein-protein interaction network of the genes involved in different pathways. The proteins which are most densely connected have been clustered through MCODE algorithm to identify the protein neighbourhoods. c) Enrichment analysis of genes-disease association represents the genes which are involved in different diseases. The images were generated using Metascape [71].