In native articular cartilage, chondrocytes (Chy) are completely capsulated by a pericellular matrix (PCM), together called the chondron (Chn). Due to its unique properties (w.r.t. territorial matrix) and importance in mechanotransduction, the PCM and Chn may be important in regenerative strategies. The current gold standard for the isolation of Chns from cartilage dates from 1997. Although previous research already showed the low cell yield and the heterogeneity of the isolated populations, their compositions and properties have never been thoroughly characterized. This study aimed to compare enzymatic isolation methods for Chy and Chns and characterizes the isolation efficiency and quality of the PCM. Bovine articular cartilage was digest...
Adult articular chondrocytes are surrounded by a pericellular matrix (PCM) to form a chondron. The P...
The number of patients suffering from osteoarthritis, resulting in loss of good human life qualities...
Adult articular chondrocytes are surrounded by a pericellular matrix (PCM) to form a chondron. The P...
In native articular cartilage, chondrocytes (Chy) are completely capsulated by a pericellular matrix...
In native articular cartilage, chondrocytes (Chy) are completely capsulated by a pericellular matrix...
OBJECTIVE: To develop and test a simple enzymatic procedure for isolating chondrons, which consist o...
SummaryObjective:To develop and test a simple enzymatic procedure for isolating chondrons, which con...
Chondrocyte transplantation has been successfully tested and proposed as a clinical procedure aiming...
SummaryObjectiveNumerous methods for isolation of human chondrocytes are reported in the literature,...
AbstractBackgroundAdvancements in cartilage tissue engineering have the potential to ameliorate faci...
SummaryObjectiveThe chondron is a basic unit of articular cartilage that includes the chondrocyte an...
The extracellular matrix surrounding chondrocytes within a chondron is likely to affect the metaboli...
OBJECTIVE: The chondron is a basic unit of articular cartilage that includes the chondrocyte and its...
OBJECTIVE: To quantitate changes in the pericellular matrix in osteoarthritic (OA) articular cartila...
Objective Interactions between chondrocytes and their native pericellular matrix provide optimal cir...
Adult articular chondrocytes are surrounded by a pericellular matrix (PCM) to form a chondron. The P...
The number of patients suffering from osteoarthritis, resulting in loss of good human life qualities...
Adult articular chondrocytes are surrounded by a pericellular matrix (PCM) to form a chondron. The P...
In native articular cartilage, chondrocytes (Chy) are completely capsulated by a pericellular matrix...
In native articular cartilage, chondrocytes (Chy) are completely capsulated by a pericellular matrix...
OBJECTIVE: To develop and test a simple enzymatic procedure for isolating chondrons, which consist o...
SummaryObjective:To develop and test a simple enzymatic procedure for isolating chondrons, which con...
Chondrocyte transplantation has been successfully tested and proposed as a clinical procedure aiming...
SummaryObjectiveNumerous methods for isolation of human chondrocytes are reported in the literature,...
AbstractBackgroundAdvancements in cartilage tissue engineering have the potential to ameliorate faci...
SummaryObjectiveThe chondron is a basic unit of articular cartilage that includes the chondrocyte an...
The extracellular matrix surrounding chondrocytes within a chondron is likely to affect the metaboli...
OBJECTIVE: The chondron is a basic unit of articular cartilage that includes the chondrocyte and its...
OBJECTIVE: To quantitate changes in the pericellular matrix in osteoarthritic (OA) articular cartila...
Objective Interactions between chondrocytes and their native pericellular matrix provide optimal cir...
Adult articular chondrocytes are surrounded by a pericellular matrix (PCM) to form a chondron. The P...
The number of patients suffering from osteoarthritis, resulting in loss of good human life qualities...
Adult articular chondrocytes are surrounded by a pericellular matrix (PCM) to form a chondron. The P...