Dexamethasone nanomedicines for COVID-19
- Lammers, Twan
- Sofias, Alexandros Marios
- van der Meel, Roy
- Schiffelers, Raymond M.
- Storm, Gert
- Tacke, Frank
- Koschmieder, Steffen
- Bruemmendorf, Tim H.
- Kiessling, F.
- Metselaar, Josbert M.
DOIAbstract
Nano-formulating dexamethasone, and administering it via intravenous injection or inhalation, may help to improve anti-COVID-19 treatment efficacy by targeting the potent corticosteroid drug to hyper-activated immune cells, by potentiating its anti-oedema activity and by exploiting its anti-fibrotic effects
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