The present study was conducted to investigate the applicability of proton microprobe techniques in the assessment of intracellular ion concentrations in individual cardiac-type H9c2 cells. Several methods to minimise the contribution of the extracellular environment were explored. Preliminary results indicate that proton microprobe techniques might be useful to assess intracellular ion concentrations in individual, cultured cells
A cells viability can be altered by the presence of bioactive materials particles and their features...
Conventional analytical procedures only permit the determination of average concentrations of cell c...
In previous studies no clear difference was found between the intra- and extra-cellular compartment ...
The present study was conducted to investigate the applicability of proton microprobe techniques in ...
Proton microprobe techniques are useful in investigating ischemia-reperfusion induced ion shifts bet...
The Eindhoven scanning proton microprobe enables the determination of the ion content of heart tissu...
Intracellular chloride ion (Cl−) is known to have various roles in the cellular growth, modulation o...
Partial exposure of single ventricular myocytes to membrane-permeant weak acids or bases, using a du...
Intracellular pH (pH(i)) is an important modulator of cardiac function. The spatial regulation of pH...
Intracellular potassium is a critical element to many vital cell processes. Thus, the ability to acc...
The ability of cells to maintain pH homeostasis in response to environmental changes has elicited in...
A cells viability can be altered by the presence of bioactive materials particles and their features...
Conventional analytical procedures only permit the determination of average concentrations of cell c...
In previous studies no clear difference was found between the intra- and extra-cellular compartment ...
The present study was conducted to investigate the applicability of proton microprobe techniques in ...
Proton microprobe techniques are useful in investigating ischemia-reperfusion induced ion shifts bet...
The Eindhoven scanning proton microprobe enables the determination of the ion content of heart tissu...
Intracellular chloride ion (Cl−) is known to have various roles in the cellular growth, modulation o...
Partial exposure of single ventricular myocytes to membrane-permeant weak acids or bases, using a du...
Intracellular pH (pH(i)) is an important modulator of cardiac function. The spatial regulation of pH...
Intracellular potassium is a critical element to many vital cell processes. Thus, the ability to acc...
The ability of cells to maintain pH homeostasis in response to environmental changes has elicited in...
A cells viability can be altered by the presence of bioactive materials particles and their features...
Conventional analytical procedures only permit the determination of average concentrations of cell c...
In previous studies no clear difference was found between the intra- and extra-cellular compartment ...