Mitochondria are the power plant of the heart, burning fat and sugars to supply the muscle with the adenosine triphosphate (ATP) free energy that drives contraction and relaxation during each heart beat. This function was first captured in a mathematical model in 1967. Today, interest in such a model has been rekindled by ongoing in silico integrative physiology efforts such as the Cardiac Physiome project. Here, the status of the field of computational modeling of mitochondrial ATP synthetic function is reviewed
Most of the adenosine triphosphate (ATP) synthesized during glucose metabolism is produced in the mi...
Oxidative phosphorylation (OXPHOS) is an oxygen-dependent process that consumes catabolized nutrient...
ABSTRACT We present an integrated thermokinetic model describing control of cardiac mitochondrial bi...
Mitochondria are the power plant of the heart, burning fat and sugars to supply the muscle with the ...
AbstractAn intricate network of reactions is involved in matching energy supply with demand in the h...
A computational model for the mitochondrial respiratory chain that appropriately balances mass, char...
In this review we analyze the recent important and remarkable advancements in studies of compartment...
International audienceIn this review we analyze the recent important and remarkable advancements in ...
International audienceThe mathematical model of the compartmentalized energy transfer system in card...
Cardiac mitochondria are intracellular organelles that play an important role in energy metabolism a...
The mathematical model of the compartmentalized energy transfer system in cardiac myocytes presented...
drion represents a unique opportunity to apply mathematical modeling to a complex biological system....
Mathematical models of mitochondrial bioenergetics provide powerful analytical tools to help interpr...
Mitochondrial bioenergetic processes are central to the production of cellular energy, and a decreas...
Mitochondrial bioenergetic processes are central to the production of cellular energy, and a decreas...
Most of the adenosine triphosphate (ATP) synthesized during glucose metabolism is produced in the mi...
Oxidative phosphorylation (OXPHOS) is an oxygen-dependent process that consumes catabolized nutrient...
ABSTRACT We present an integrated thermokinetic model describing control of cardiac mitochondrial bi...
Mitochondria are the power plant of the heart, burning fat and sugars to supply the muscle with the ...
AbstractAn intricate network of reactions is involved in matching energy supply with demand in the h...
A computational model for the mitochondrial respiratory chain that appropriately balances mass, char...
In this review we analyze the recent important and remarkable advancements in studies of compartment...
International audienceIn this review we analyze the recent important and remarkable advancements in ...
International audienceThe mathematical model of the compartmentalized energy transfer system in card...
Cardiac mitochondria are intracellular organelles that play an important role in energy metabolism a...
The mathematical model of the compartmentalized energy transfer system in cardiac myocytes presented...
drion represents a unique opportunity to apply mathematical modeling to a complex biological system....
Mathematical models of mitochondrial bioenergetics provide powerful analytical tools to help interpr...
Mitochondrial bioenergetic processes are central to the production of cellular energy, and a decreas...
Mitochondrial bioenergetic processes are central to the production of cellular energy, and a decreas...
Most of the adenosine triphosphate (ATP) synthesized during glucose metabolism is produced in the mi...
Oxidative phosphorylation (OXPHOS) is an oxygen-dependent process that consumes catabolized nutrient...
ABSTRACT We present an integrated thermokinetic model describing control of cardiac mitochondrial bi...