Space-filling curves can be used to organise points in the plane into bounding-box hierarchies (such as R-trees). We develop measures of the bounding-box quality of space-filling curves that express how effective different space-filling curves are for this purpose. We give general lower bounds on the bounding-box quality measures and on locality according to Gotsman and Lindenbaum for a large class of space-filling curves. We describe a generic algorithm to approximate these and similar quality measures for any given curve. Using our algorithm we find good approximations of the locality and the bounding-box quality of several known and new space-filling curves. Surprisingly, some curves with relatively bad locality by Gotsman and Lindenbaum...