As single-cell RNA sequencing techniques improve and more cells are measured in individual experiments, cell clustering procedures become increasingly more computationally intensive. This paper studies the runtime performance impact of a specialized clustering algorithm for data converted to a binary format, in order to reduce computational burden. We experimentally show that our specialized algorithm runs faster than the Seurat library on small datasets, and that with proper dimensionality reduction and approximation techniques, the algorithm could be more scalable than current methods. Optimizations for cluster quality and memory efficiency are not considered in this paper.CSE3000 Research ProjectComputer Science and Engineerin
Single-cell sequencing provides novel means to interpret the transcriptomic profiles of individual c...
The process by which DNA is transformed into gene products, such as RNA and proteins, is called gene...
Abstract Background With the recent proliferation of single-cell RNA-Seq experiments, several method...
Analysing single-cell RNA sequencing data is becoming an increasingly tedious task as the size of da...
The rapid increase in the size of single-cell RNAseq datasets presents significant performance chall...
Single-cell RNA-seq (scRNAseq) is a powerful tool to study heterogeneity of cells. Recently, several...
###EgeUn###A number of specialized clustering methods have been developed so far for the accurate an...
Background: The commercially available 10x Genomics protocol to generate droplet-based single cell R...
SUNER, ASLI/0000-0002-6872-9901WOS: 000491222300003PubMed: 31646845A number of specialized clusterin...
Currently, clustering applications use classical methods to partition a set of data (or objects) in ...
Background: The commercially available 10x Genomics protocol to generate droplet-based single cell R...
Subpopulation identification, usually via some form of unsupervised clustering, is a fundamental ste...
Single Cell RNA sequencing (SCRNA-SEQ) enables researchers to gain insights into complex biological ...
The most recent approaches for clustering single-cell RNA-sequencing data rely on deep auto-encoders...
In recent years, Single cell RNA sequencing (scRNA-Seq) has become widely popular in bioinformatics....
Single-cell sequencing provides novel means to interpret the transcriptomic profiles of individual c...
The process by which DNA is transformed into gene products, such as RNA and proteins, is called gene...
Abstract Background With the recent proliferation of single-cell RNA-Seq experiments, several method...
Analysing single-cell RNA sequencing data is becoming an increasingly tedious task as the size of da...
The rapid increase in the size of single-cell RNAseq datasets presents significant performance chall...
Single-cell RNA-seq (scRNAseq) is a powerful tool to study heterogeneity of cells. Recently, several...
###EgeUn###A number of specialized clustering methods have been developed so far for the accurate an...
Background: The commercially available 10x Genomics protocol to generate droplet-based single cell R...
SUNER, ASLI/0000-0002-6872-9901WOS: 000491222300003PubMed: 31646845A number of specialized clusterin...
Currently, clustering applications use classical methods to partition a set of data (or objects) in ...
Background: The commercially available 10x Genomics protocol to generate droplet-based single cell R...
Subpopulation identification, usually via some form of unsupervised clustering, is a fundamental ste...
Single Cell RNA sequencing (SCRNA-SEQ) enables researchers to gain insights into complex biological ...
The most recent approaches for clustering single-cell RNA-sequencing data rely on deep auto-encoders...
In recent years, Single cell RNA sequencing (scRNA-Seq) has become widely popular in bioinformatics....
Single-cell sequencing provides novel means to interpret the transcriptomic profiles of individual c...
The process by which DNA is transformed into gene products, such as RNA and proteins, is called gene...
Abstract Background With the recent proliferation of single-cell RNA-Seq experiments, several method...