We sought to investigate differential phenotypic characteristics according to neutrophil counts, using a biostatistics approach in a large-cohort study from the Spanish Online Bronchiectasis Registry (RIBRON). The 1034 patients who met the inclusion criteria were clustered into two groups on the basis of their blood neutrophil levels. Using the Mann-Whitney U test to explore potential differences according to FACED and EFACED scores between the two groups, a neutrophil count of 4990 cells/µL yielded the most balanced cluster sizes: (1) above-threshold (n = 337) and (2) below-threshold (n = 697) groups. Patients above the threshold showed significantly worse lung function parameters and nutritional status, while systemic inflammation levels ...
Altres ajuts: Fondo Europeo de Desarrollo Regional (FEDER); CIBERES (ISC-III); SEPAR 2020; ZAMBON-PH...
Rationale: Bronchiectasis is classically considered a neutrophilic disorder, but eosinophilic subtyp...
Bronchiectasis is a heterogeneous disease. This study aimed at identifying discrete groups of patien...
We sought to investigate differential phenotypic characteristics according to neutrophil counts, usi...
We sought to investigate differential phenotypic characteristics according to neutrophil counts, usi...
We sought to investigate differential phenotypic characteristics according to neutrophil counts, usi...
Altres ajuts: Fondo Europeo de Desarrollo Regional (FEDER); CIBERES; SEPAR 2020; ZAMBON-PHARMA, Spai...
Differential phenotypic characteristics using data mining approaches were defined in a large cohort ...
Differential phenotypic characteristics using data mining approaches were defined in a large cohort ...
Whether high blood eosinophil counts may define a better phenotype in bronchiectasis patients, as sh...
Whether high blood eosinophil counts may define a better phenotype in bronchiectasis patients, as sh...
Whether high blood eosinophil counts may define a better phenotype in bronchiectasis patients, as sh...
We hypothesized that systemic inflammatory and nutritional parameters may differ between male and fe...
Rationale: Although inflammation and infection are key disease drivers in bronchiectasis, few studie...
Altres ajuts: Fondo Europeo de Desarrollo Regional (FEDER); CIBERES (ISC-III); SEPAR 2020; ZAMBON-PH...
Rationale: Bronchiectasis is classically considered a neutrophilic disorder, but eosinophilic subtyp...
Bronchiectasis is a heterogeneous disease. This study aimed at identifying discrete groups of patien...
We sought to investigate differential phenotypic characteristics according to neutrophil counts, usi...
We sought to investigate differential phenotypic characteristics according to neutrophil counts, usi...
We sought to investigate differential phenotypic characteristics according to neutrophil counts, usi...
Altres ajuts: Fondo Europeo de Desarrollo Regional (FEDER); CIBERES; SEPAR 2020; ZAMBON-PHARMA, Spai...
Differential phenotypic characteristics using data mining approaches were defined in a large cohort ...
Differential phenotypic characteristics using data mining approaches were defined in a large cohort ...
Whether high blood eosinophil counts may define a better phenotype in bronchiectasis patients, as sh...
Whether high blood eosinophil counts may define a better phenotype in bronchiectasis patients, as sh...
Whether high blood eosinophil counts may define a better phenotype in bronchiectasis patients, as sh...
We hypothesized that systemic inflammatory and nutritional parameters may differ between male and fe...
Rationale: Although inflammation and infection are key disease drivers in bronchiectasis, few studie...
Altres ajuts: Fondo Europeo de Desarrollo Regional (FEDER); CIBERES (ISC-III); SEPAR 2020; ZAMBON-PH...
Rationale: Bronchiectasis is classically considered a neutrophilic disorder, but eosinophilic subtyp...
Bronchiectasis is a heterogeneous disease. This study aimed at identifying discrete groups of patien...