Western blots on (A) engineered HCC1806 and SUM159 cells with 0.5 μg/ml Dox-induced overexpression of MAPK4 (iMAPK4) or control (iCtrl) treated with MNK1/2 inhibitors SLV-2436 (2 μm), eFT-508 (1 μm), or DMSO control for 24 h and (B) WT and MAPK4-KO SUM159 and MDA-MB-231 cells treated with MNK1/2 inhibitors SLV-2436 (2 μm), eFT-508 (1 μm), or DMSO control for 24 h. Proliferation assays on (C) engineered HCC1806 and SUM159 cells with 0.5 μg/ml Dox-induced overexpression of MAPK4 (iMAPK4) or control (iCtrl) and (D) WT and MAPK4-KO MDA-MB-231 cells treated with MNK1/2 inhibitors SLV-2436 (2 μm), eFT-508 (1 μm), or DMSO control. Quantification data as means ± SD. Data are representative of at least 3 independent experiments. The numerical values...
(A) Plate colony formation assays and (B) soft-agar assays on WT or engineered MAPK4-KO SUM159 and M...
(A) Western blots showing the kinetics of Med16-AID depletion and stability of TBP-3xFLAG-MNase upon...
<p>The upper side of panel (A) shows a representative Western blot for Phospho-p44/42 MAPK (Erk1/2) ...
Western blots on (A) engineered HCC1806 and SUM159 cells with 0.5 μg/ml Dox-induced overexpression o...
(A) Western blots on engineered HCC1806 and SUM159 cells with 0.5 μg/ml Dox-induced overexpression o...
(A) qPCR for PDK1 mRNA expression in the engineered SUM159 cells with 0.5 μg/ml Dox-induced overexpr...
Plate colony formation assays on the WT vs. MAPK4-knockout (KO, #2) vs. MAPK4-knockout with rescued ...
(A) Western blots, (B) proliferation assays, (C) plate colony formation assays, and (D) soft-agar as...
(A) Western blot on the engineered SUM159 and HCC1806 cells with 0.5 μg/ml Dox-induced overexpressio...
(A) Proliferation assays, (B) plate colony formation assays, and (C) soft-agar assays on the enginee...
(A) Western blots, (B) proliferation assays, (C, D) plate clonogenic assays, and (E, F) soft-agar as...
Western blots on (A) engineered SUM159, MDA-MB-436, MDA-MB-468, HCC1395, and HCC1806 cells with 0....
Western blots on PDK1 protein expression in (A) the engineered H157 cells with 4 μg/ml Dox-induced k...
(A) Plate colony formation assays and (B) soft-agar assays on the engineered SUM159 and HCC1806 cell...
(A) Western blots, (B) proliferation assays, (C) plate colony formation assays, and (D) soft-agar as...
(A) Plate colony formation assays and (B) soft-agar assays on WT or engineered MAPK4-KO SUM159 and M...
(A) Western blots showing the kinetics of Med16-AID depletion and stability of TBP-3xFLAG-MNase upon...
<p>The upper side of panel (A) shows a representative Western blot for Phospho-p44/42 MAPK (Erk1/2) ...
Western blots on (A) engineered HCC1806 and SUM159 cells with 0.5 μg/ml Dox-induced overexpression o...
(A) Western blots on engineered HCC1806 and SUM159 cells with 0.5 μg/ml Dox-induced overexpression o...
(A) qPCR for PDK1 mRNA expression in the engineered SUM159 cells with 0.5 μg/ml Dox-induced overexpr...
Plate colony formation assays on the WT vs. MAPK4-knockout (KO, #2) vs. MAPK4-knockout with rescued ...
(A) Western blots, (B) proliferation assays, (C) plate colony formation assays, and (D) soft-agar as...
(A) Western blot on the engineered SUM159 and HCC1806 cells with 0.5 μg/ml Dox-induced overexpressio...
(A) Proliferation assays, (B) plate colony formation assays, and (C) soft-agar assays on the enginee...
(A) Western blots, (B) proliferation assays, (C, D) plate clonogenic assays, and (E, F) soft-agar as...
Western blots on (A) engineered SUM159, MDA-MB-436, MDA-MB-468, HCC1395, and HCC1806 cells with 0....
Western blots on PDK1 protein expression in (A) the engineered H157 cells with 4 μg/ml Dox-induced k...
(A) Plate colony formation assays and (B) soft-agar assays on the engineered SUM159 and HCC1806 cell...
(A) Western blots, (B) proliferation assays, (C) plate colony formation assays, and (D) soft-agar as...
(A) Plate colony formation assays and (B) soft-agar assays on WT or engineered MAPK4-KO SUM159 and M...
(A) Western blots showing the kinetics of Med16-AID depletion and stability of TBP-3xFLAG-MNase upon...
<p>The upper side of panel (A) shows a representative Western blot for Phospho-p44/42 MAPK (Erk1/2) ...