The toxicity of any drug against normal cells is a health hazard for all humans. At present, health and disease researchers from all over the world are trying to synthesize designer drugs with diminished toxicity and side effects. The purpose of the present study is to enhance the bioavailability and biocompatibility of gemcitabine (GEM) by decreasing its toxicity and reducing deamination during drug delivery by incorporating it inside the hydrophobic cavity of β-cyclodextrin (β-CD) without affecting the drug ability of the parent compound (GEM). The newly synthesized inclusion complex (IC) was characterized by different physical and spectroscopic techniques, thereby confirming the successful incorporation of the GEM molecule into the nanoc...
Long term intake of antituberculosis drugs will lead to severe adverse reactions that will ultimatel...
Photodynamic therapy is an emerging treatment of tumor diseases. The complexes with γ-cyclodextrins ...
In this article, we have addressed to a demanding physicochemical aspect of therapeutic and drug res...
The toxicity of any drug against normal cells is a health hazard for all humans. At present, health ...
The chemotherapeutic gemcitabine was actively and stably loaded into lipid nanoparticles through the...
Current cancer chemotherapies commonly suffer from nonspecificity, drug resistance, poor bioavailabi...
AbstractGemcitabine is an anticancer nucleoside analogue active against a wide variety of solid tumo...
International audienceAiming to engineer simple, neutral, strongly amphiphilic photoactive nanoparti...
Pancreatic ductal adenocarcinoma (PDAC), often known as pancreatic cancer, is one of the main causes...
The main objective is to formulate solid lipid nanoparticles conjugated with cyclic RGDfk peptide en...
Dual enzymatic reactions were introduced to fabricate programmed gemcitabine (GEM) nanovectors for t...
This study was aimed to evaluate the impact of water-soluble β-cyclodextrin polymer (β-CDP), as a ...
The chemotherapeutic gemcitabine was actively and stably loaded into lipid nanoparticles through the...
International audienceTemoporfin (meta-tetrakis(3-hydroxyphenyl)chlorin, mTHPC) is one of the most p...
Purpose: The present study reports a novel conjugate of gemcitabine (GEM) with bovine serum albumin ...
Long term intake of antituberculosis drugs will lead to severe adverse reactions that will ultimatel...
Photodynamic therapy is an emerging treatment of tumor diseases. The complexes with γ-cyclodextrins ...
In this article, we have addressed to a demanding physicochemical aspect of therapeutic and drug res...
The toxicity of any drug against normal cells is a health hazard for all humans. At present, health ...
The chemotherapeutic gemcitabine was actively and stably loaded into lipid nanoparticles through the...
Current cancer chemotherapies commonly suffer from nonspecificity, drug resistance, poor bioavailabi...
AbstractGemcitabine is an anticancer nucleoside analogue active against a wide variety of solid tumo...
International audienceAiming to engineer simple, neutral, strongly amphiphilic photoactive nanoparti...
Pancreatic ductal adenocarcinoma (PDAC), often known as pancreatic cancer, is one of the main causes...
The main objective is to formulate solid lipid nanoparticles conjugated with cyclic RGDfk peptide en...
Dual enzymatic reactions were introduced to fabricate programmed gemcitabine (GEM) nanovectors for t...
This study was aimed to evaluate the impact of water-soluble β-cyclodextrin polymer (β-CDP), as a ...
The chemotherapeutic gemcitabine was actively and stably loaded into lipid nanoparticles through the...
International audienceTemoporfin (meta-tetrakis(3-hydroxyphenyl)chlorin, mTHPC) is one of the most p...
Purpose: The present study reports a novel conjugate of gemcitabine (GEM) with bovine serum albumin ...
Long term intake of antituberculosis drugs will lead to severe adverse reactions that will ultimatel...
Photodynamic therapy is an emerging treatment of tumor diseases. The complexes with γ-cyclodextrins ...
In this article, we have addressed to a demanding physicochemical aspect of therapeutic and drug res...