Synthesis of fasicularin

Kaga, Atsushi
Tnay, Ya Lin
Chiba, Shunsuke

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Publication date

January 2016

DOI

10.1021/acs.orglett.6b01669

Journal

Organic Letters

Abstract

The synthesis of a tricyclic marine alkaloid, fasicularin, was accomplished. Stereoselective synthesis of the aza-spirocyclic BC-ring precursor and ensuing construction of the A-ring with stereocontrolled installation of the C2 hexyl group feature prominently in the synthesis.Ministry of Education (MOE)Nanyang Technological UniversityAccepted versionThis work was supported by funding from Nanyang Technological University and the Singapore Ministry of Education and Singapore Ministry of Education (Academic Research Fund Tier 1: RG4/13)

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Synthesis of fasicularin

Abstract

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Synthesis of fasicularin

Abstract

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