Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort

Skin diseases impact significantly on the quality of life and psychology of patients. Obesity has been observed as a risk factor for skin diseases. Skin epidermal barrier dysfunctions are typical manifestations across several dermatological disturbances.Ministry of Health (MOH)National Medical Research Council (NMRC)Published versionThis work was supported by the Singapore Ministry of Health’s National Medical Research Council under its OF-LCG funding scheme (NMRC Project Ref. MOH-000271-00) and intramural funding from Nanyang Technological University, Lee Kong Chian School of Medicine and the National Healthcare Group. Dr. Yik Weng Yew is supported by the Singapore Ministry of Health’s National Medical Research Council under its Transition Award funding scheme (NMRC Project Ref. NMRC/ MOH-TA19nov-0004). Professor John Chambers is supported by the Singapore Ministry of Health’s National Medical Research Council under its STaR funding scheme (NMRC Project Ref. NMRC/STaR/0028/2017)