Sulfur can form diverse S(IV) and S(VI) stereogenic centers, of which some have gained significant attention recently due to their increasing use as pharmacophores in drug discovery programs. The preparation of these sulfur stereogenic centers in their enantiopure form has been challenging, and progress made will be discussed in this Perspective. This Perspective summarizes different strategies, with selected works, for asymmetric synthesis of these moieties, including diastereoselective transformations using chiral auxiliaries, enantiospecific transformations of enantiopure sulfur compounds, and catalytic enantioselective synthesis. We will discuss the advantages and limitations of these strategies and will provide our views on how this fi...
Easily accessible chiral sulfinamide 2 has been developed as the first highly efficient and enantios...
A significant limitation of modern asymmetric catalysis is that, when applied to processes that gene...
Enantiomerically pure P-tolyl sulphinyl-N,N-dimethylthioacetamide (1) was prepared starting from (-)...
This thesis reports findings in two projects utilising sulfur as a chiral auxiliary in asymmetric sy...
Enantiomerically pure tertiary thiols provide a major synthetic challenge, and despite the importanc...
C-H functionalization has been established as an efficient way to generate molecular complexity. The...
Catalytic asymmetric [2,3] sigmatropic rearrangement of sulfur ylides generated from aryldiazoacetat...
Methods for establishing the absolute configuration of sulfur-stereogenic aza-sulfur derivatives are...
Sulfur-based ylides are very important and valuable reagents in organic synthesis and have been wide...
The aldol-type condensation of enantiomerically pure \u3b1-sulphinylacetamides is described. The ste...
We report a new process to access highly enantioenriched sulfur-based heterocycles by an asymmetric ...
Asymmetric Synthesis of ß-Hydroxythioacetamides mediated by Enantiomerically Pure Sulphinyl Derivati...
The trifluoromethylthio (SCF3) functional group has been of increasing importance in drug design and...
Three different kinds of sulfur containing electrophiles in organo- and metal catalyzed reactions ha...
For the first time, chiral sulfoximine derivatives have been applied as asymmetric organocatalysts. ...
Easily accessible chiral sulfinamide 2 has been developed as the first highly efficient and enantios...
A significant limitation of modern asymmetric catalysis is that, when applied to processes that gene...
Enantiomerically pure P-tolyl sulphinyl-N,N-dimethylthioacetamide (1) was prepared starting from (-)...
This thesis reports findings in two projects utilising sulfur as a chiral auxiliary in asymmetric sy...
Enantiomerically pure tertiary thiols provide a major synthetic challenge, and despite the importanc...
C-H functionalization has been established as an efficient way to generate molecular complexity. The...
Catalytic asymmetric [2,3] sigmatropic rearrangement of sulfur ylides generated from aryldiazoacetat...
Methods for establishing the absolute configuration of sulfur-stereogenic aza-sulfur derivatives are...
Sulfur-based ylides are very important and valuable reagents in organic synthesis and have been wide...
The aldol-type condensation of enantiomerically pure \u3b1-sulphinylacetamides is described. The ste...
We report a new process to access highly enantioenriched sulfur-based heterocycles by an asymmetric ...
Asymmetric Synthesis of ß-Hydroxythioacetamides mediated by Enantiomerically Pure Sulphinyl Derivati...
The trifluoromethylthio (SCF3) functional group has been of increasing importance in drug design and...
Three different kinds of sulfur containing electrophiles in organo- and metal catalyzed reactions ha...
For the first time, chiral sulfoximine derivatives have been applied as asymmetric organocatalysts. ...
Easily accessible chiral sulfinamide 2 has been developed as the first highly efficient and enantios...
A significant limitation of modern asymmetric catalysis is that, when applied to processes that gene...
Enantiomerically pure P-tolyl sulphinyl-N,N-dimethylthioacetamide (1) was prepared starting from (-)...