Analysis of selected target genes of the ciliogenic transcription factor FoxJ1, LIM Yen Wei Cilia are hair-like protrusions extending from membranes. They are formed from basal bodies and elongate to form axonemes, via a process called ciliogenesis. Disruption in proteins involved in motile cilia, such as dynein, result in ciliopathies such as primary ciliary dyskinesia. We are interested in 7 genes downstream of FoxJ1, which is a master regulator of ciliogenesis. We hypothesise that these genes may localize to the cilia, highlighting the importance of these genes in ciliogenesis. RNA of these genes were made and injected into zebrafish embryos. At least one gene, tmprss13b, was found to localize to the cilia via confocal microscopy....
The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wi...
The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wi...
The cilium is an essential organelle at the surface of most mammalian cells whose dysfunction causes...
Analysis of selected target genes of the ciliogenic transcription factor FoxJ1, LIM Yen Wei C...
It is generally believed that the last eukaryotic common ancestor (LECA) was a unicellular organism ...
<div><p>It is generally believed that the last eukaryotic common ancestor (LECA) was a unicellular o...
It is generally believed that the last eukaryotic common ancestor (LECA) was a unicellular organism ...
It is generally believed that the last eukaryotic common ancestor (LECA) was a unicellular organism ...
It is generally believed that the last eukaryotic common ancestor (LECA) was a unicellular organism ...
It is generally believed that the last eukaryotic common ancestor (LECA) was a unicellular organism ...
Developmental defects in motile cilia, arising from genetic abnormalities in one or more ciliary gen...
Abstract It is generally believed that the last eukaryotic common ancestor (LECA) was a unicellular ...
Developmental defects in motile cilia, arising from genetic abnormalities in one or more ciliary gen...
The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wi...
The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wi...
The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wi...
The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wi...
The cilium is an essential organelle at the surface of most mammalian cells whose dysfunction causes...
Analysis of selected target genes of the ciliogenic transcription factor FoxJ1, LIM Yen Wei C...
It is generally believed that the last eukaryotic common ancestor (LECA) was a unicellular organism ...
<div><p>It is generally believed that the last eukaryotic common ancestor (LECA) was a unicellular o...
It is generally believed that the last eukaryotic common ancestor (LECA) was a unicellular organism ...
It is generally believed that the last eukaryotic common ancestor (LECA) was a unicellular organism ...
It is generally believed that the last eukaryotic common ancestor (LECA) was a unicellular organism ...
It is generally believed that the last eukaryotic common ancestor (LECA) was a unicellular organism ...
Developmental defects in motile cilia, arising from genetic abnormalities in one or more ciliary gen...
Abstract It is generally believed that the last eukaryotic common ancestor (LECA) was a unicellular ...
Developmental defects in motile cilia, arising from genetic abnormalities in one or more ciliary gen...
The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wi...
The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wi...
The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wi...
The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wi...
The cilium is an essential organelle at the surface of most mammalian cells whose dysfunction causes...