Diastereoselective intramolecular hydride transfer triggered by electrophilic halogenation of aryl alkenes

Diastereoselective hydride transfer could be triggered by electrophilic halogenation (bromination or fluorination) of homoallylic alcohol O-Bn ethers. The resulting diastereomerically enriched haloalkyl alcohols underwent subsequent intramolecular nucleophilic substitution to afford the corresponding tetrahydrofurans.Ministry of Education (MOE)Nanyang Technological UniversityAccepted versionThis work was supported by funding from Nanyang Technological University (for S.C.), the Singapore Ministry of Education (Academic Research Fund Tier 1: RG2/18 for S.C.), the University of Ottawa (for F.G.), and the Natural Sciences and Engineering Research Council (for F.G.)