Protocolo-Side effects of atypical antipsychotics. A systematic review.pdf

Atypical antipsychotics, also known as second-generation antipsychotics, have revolutionized the treatment of psychotic disorders in recent decades. These medications have demonstrated efficacy in controlling both positive and negative symptoms of schizophrenia, as well as in the treatment of other psychotic disorders. However, despite their therapeutic benefits, atypical antipsychotics are also associated with a range of side effects. In this review, we aim to examine the most common adverse effects associated with the use of atypical antipsychotics in patients. It is important to note that the incidence and severity of these effects may vary among different atypical antipsychotic agents and also among individuals receiving treatment. However, there are some adverse effects that have been reported more frequently and warrant special attention. One of the most common adverse effects is weight gain and alteration of lipid metabolism. Certain atypical antipsychotics, such as olanzapine and clozapine, have been associated with an increased risk of weight gain, dyslipidemia, and the development of metabolic syndrome. These effects may predispose patients to cardiovascular diseases and type 2 diabetes, needing careful monitoring and appropriate management strategies.