Read coverage metrics of the <i>B. melitensis</i> pan-genome.

a) Distribution of mean contig coverages of the ancient B. melitensis assembly. The dashed line indicates the mean coverage while the shaded rectangle indicates ±2 standard deviations from the mean. Arrows indicate contigs with a significantly greater read depth. b) GC bias correction results for the mapped contigs. c) Circos plot of the ten largest contigs in the ancient B. melitensis assembly. The outer ring indicates the mean read depth over a 0.5% sliding window whereas the inner ring is the GC content over the same period.