Abstract Among numerous approaches to the study of migraine, the nitroglycerin (NTG) model occupies a prominent place, but there is relatively insufficient information about how NTG affects intracranial vessels. In this study we aim to assess the effects of NTG on blood-flow parameters in meningeal vessels measured by imaging photoplethysmography (iPPG) in animal experiments. An amplitude of the pulsatile component (APC) of iPPG waveform was assessed before and within 2.5 h after the NTG administration in saline (n = 13) or sumatriptan (n = 12) pretreatment anesthetized rats in conditions of a closed cranial window. In animals of both groups, NTG caused a steady decrease in blood pressure. In 7 rats of the saline group, NTG resulted in prog...
Systemic administration of nitroglycerin (NTG), a nitric oxide (NO) donor, in migraineurs triggers a...
Migraine is a paroxysmal neurovascular disorder, which affects a significant proportion of the popu...
Non-steroidal anti-inflammatory drugs (NSAIDs) that act as cyclo-oxygenase (COX) inhibitors are comm...
Migraine is a disease for which there is still no defined pathophysiological etiology and few transl...
Migraine attacks occur spontaneously in those who suffer from the condition, but migraine-like attac...
<div><p>Vascular changes underlying headache in migraine patients induced by Glyceryl trinitrate (GT...
The demonstration that nitrovasodilators act as nitric oxide (NO) donors has favored a resurgence of...
Nitroglycerin (glycerol trinitrate, GTN) induces headache in migraineurs, an effect that has been us...
When administered to migraine patients, nitroglycerin induces a spontaneous-like migraine attack, wi...
Migraine is a paroxysmal neurovascular disorder, which affects a significant proportion of the popul...
Background: The complex pathophysiology of migraine is not yet clearly understood; therefore, experi...
BackgroundSystemic nitroglycerin (NTG) activates brain nuclei involved in nociceptive transmission a...
Systemic nitroglycerin (NTG) activates brain nuclei involved in nociceptive transmission as well as ...
Background/aim: Chronic migraine is a common debilitating disease with limited treatment options. We...
The supratentorial cerebral dura of the albino rat is equipped with a rich sensory innervation both ...
Systemic administration of nitroglycerin (NTG), a nitric oxide (NO) donor, in migraineurs triggers a...
Migraine is a paroxysmal neurovascular disorder, which affects a significant proportion of the popu...
Non-steroidal anti-inflammatory drugs (NSAIDs) that act as cyclo-oxygenase (COX) inhibitors are comm...
Migraine is a disease for which there is still no defined pathophysiological etiology and few transl...
Migraine attacks occur spontaneously in those who suffer from the condition, but migraine-like attac...
<div><p>Vascular changes underlying headache in migraine patients induced by Glyceryl trinitrate (GT...
The demonstration that nitrovasodilators act as nitric oxide (NO) donors has favored a resurgence of...
Nitroglycerin (glycerol trinitrate, GTN) induces headache in migraineurs, an effect that has been us...
When administered to migraine patients, nitroglycerin induces a spontaneous-like migraine attack, wi...
Migraine is a paroxysmal neurovascular disorder, which affects a significant proportion of the popul...
Background: The complex pathophysiology of migraine is not yet clearly understood; therefore, experi...
BackgroundSystemic nitroglycerin (NTG) activates brain nuclei involved in nociceptive transmission a...
Systemic nitroglycerin (NTG) activates brain nuclei involved in nociceptive transmission as well as ...
Background/aim: Chronic migraine is a common debilitating disease with limited treatment options. We...
The supratentorial cerebral dura of the albino rat is equipped with a rich sensory innervation both ...
Systemic administration of nitroglycerin (NTG), a nitric oxide (NO) donor, in migraineurs triggers a...
Migraine is a paroxysmal neurovascular disorder, which affects a significant proportion of the popu...
Non-steroidal anti-inflammatory drugs (NSAIDs) that act as cyclo-oxygenase (COX) inhibitors are comm...