Transcranial magnetic stimulation (TMS) methods such as cortico-cortical paired associative stimulation (ccPAS) can increase the strength of functional connectivity between ventral premotor cortex (PMv) and primary motor cortex (M1) via spike timing-dependent plasticity (STDP), leading to enhanced motor functions in young adults. However, whether this STDP-inducing protocol is effective in the aging brain remains unclear. In two groups of young and elderly healthy adults, we evaluated manual dexterity with the 9-hole peg task before and after ccPAS of the left PMv-M1 circuit. We observed that ccPAS enhanced dexterity in young adults, and this effect was anticipated by a progressive increase in motor-evoked potentials (MEPs) during ccPAS adm...
A fundamental feature of the human cortex is the capability to express plastic changes that seem to ...
Brain stimulation techniques capable of optimizing cortical plasticity may provide the key to improv...
Numerous studies have reported that plasticity induced in the motor cortex by transcranial magnetic ...
Transcranial magnetic stimulation (TMS) methods such as cortico-cortical paired associative stimulat...
Aging is commonly associated with a decline in motor control and neural plasticity. Tuning cortico–c...
Objective: To examine the effect of priming paired associative stimulation (PAS) on the modulation o...
Aging is associated with changes in the motor system that, over time, can lead to functional impairm...
First published: 16 May 2023Previous research using transcranial magnetic stimulation (TMS) has demo...
Older adults have been shown to exhibit a reduction in the lateralization of neural activity. Althou...
Previous studies with transcranial magnetic stimulation (TMS) have shown that advancing age may infl...
Abstract not availableGeorge M. Opie, Eleni Vosnakis, Michael C. Ridding, Ulf Ziemann, John G. Semml...
Deterioration of motor and cognitive performance with advancing age is well documented, but its caus...
Aging is associated with reduced neuromuscular function, which may be due in part to altered cortico...
Cortico-cortical paired associative stimulation (ccPAS) is an effective transcranial magnetic stimul...
The aim of this study was to examine corticomotor excitability and plasticity following repetitive t...
A fundamental feature of the human cortex is the capability to express plastic changes that seem to ...
Brain stimulation techniques capable of optimizing cortical plasticity may provide the key to improv...
Numerous studies have reported that plasticity induced in the motor cortex by transcranial magnetic ...
Transcranial magnetic stimulation (TMS) methods such as cortico-cortical paired associative stimulat...
Aging is commonly associated with a decline in motor control and neural plasticity. Tuning cortico–c...
Objective: To examine the effect of priming paired associative stimulation (PAS) on the modulation o...
Aging is associated with changes in the motor system that, over time, can lead to functional impairm...
First published: 16 May 2023Previous research using transcranial magnetic stimulation (TMS) has demo...
Older adults have been shown to exhibit a reduction in the lateralization of neural activity. Althou...
Previous studies with transcranial magnetic stimulation (TMS) have shown that advancing age may infl...
Abstract not availableGeorge M. Opie, Eleni Vosnakis, Michael C. Ridding, Ulf Ziemann, John G. Semml...
Deterioration of motor and cognitive performance with advancing age is well documented, but its caus...
Aging is associated with reduced neuromuscular function, which may be due in part to altered cortico...
Cortico-cortical paired associative stimulation (ccPAS) is an effective transcranial magnetic stimul...
The aim of this study was to examine corticomotor excitability and plasticity following repetitive t...
A fundamental feature of the human cortex is the capability to express plastic changes that seem to ...
Brain stimulation techniques capable of optimizing cortical plasticity may provide the key to improv...
Numerous studies have reported that plasticity induced in the motor cortex by transcranial magnetic ...