The responses of neurons in the visual cortex (V1) of adult mammals have long been thought to be stable over long periods. Here, we investigated whether repeated exposure to specific stimuli would enhance V1 visual responses in mice using intrinsic signal imaging through the intact skull and two-photon imaging of calcium signals in single neurons. Mice ran on Styrofoam balls floating on air while viewing one of three different, high-contrast visual stimuli. V1 responses to the stimuli that were viewed by the animal were specifically enhanced, while responses to other stimuli were unaffected. Similar exposure in stationary mice or in mice in which NMDA receptors were partially blocked did not significantly enhance responses. These findings i...
Visual cortical neurons fire at higher rates to visual stimuli during locomotion than during immobil...
Sensory processing is dependent upon behavioral state. In mice, locomotion is accompanied by changes...
Running profoundly alters stimulus-response properties in mouse primary visual cortex (V1), but its ...
Neurons in mouse primary visual cortex (V1) are selective for particular properties of visual stimul...
SummaryBackgroundNeural responses in visual cortex depend not only on sensory input but also on beha...
The brain’s response to sensory input is strikingly modulated by behavioral state. Notably, the visu...
The brain's response to sensory input is strikingly modulated by behavioral state. Notably, the visu...
Neurons in the visual cortex were first found to be exquisitely selective for particular properties ...
SummaryThe brain’s response to sensory input is strikingly modulated by behavioral state. Notably, t...
SummaryStudies of visual processing in rodents have conventionally been performed on anesthetized an...
Sensory perception is context dependent and is likely modulated by task demands, learning and engage...
UnlabelledWe do not fully understand how behavioral state modulates the processing and transmission ...
During locomotion, visual cortical neurons fire at higher rates to visual stimuli than during immobi...
SummarySensory processing is dependent upon behavioral state. In mice, locomotion is accompanied by ...
Most of our knowledge about vision comes from experiments in which stimuli are presented to immobile...
Visual cortical neurons fire at higher rates to visual stimuli during locomotion than during immobil...
Sensory processing is dependent upon behavioral state. In mice, locomotion is accompanied by changes...
Running profoundly alters stimulus-response properties in mouse primary visual cortex (V1), but its ...
Neurons in mouse primary visual cortex (V1) are selective for particular properties of visual stimul...
SummaryBackgroundNeural responses in visual cortex depend not only on sensory input but also on beha...
The brain’s response to sensory input is strikingly modulated by behavioral state. Notably, the visu...
The brain's response to sensory input is strikingly modulated by behavioral state. Notably, the visu...
Neurons in the visual cortex were first found to be exquisitely selective for particular properties ...
SummaryThe brain’s response to sensory input is strikingly modulated by behavioral state. Notably, t...
SummaryStudies of visual processing in rodents have conventionally been performed on anesthetized an...
Sensory perception is context dependent and is likely modulated by task demands, learning and engage...
UnlabelledWe do not fully understand how behavioral state modulates the processing and transmission ...
During locomotion, visual cortical neurons fire at higher rates to visual stimuli than during immobi...
SummarySensory processing is dependent upon behavioral state. In mice, locomotion is accompanied by ...
Most of our knowledge about vision comes from experiments in which stimuli are presented to immobile...
Visual cortical neurons fire at higher rates to visual stimuli during locomotion than during immobil...
Sensory processing is dependent upon behavioral state. In mice, locomotion is accompanied by changes...
Running profoundly alters stimulus-response properties in mouse primary visual cortex (V1), but its ...