This workshop addressed challenges of clinical research in neurosurgery. Randomized controlled clinical trials (RCTs) have high internal validity, but often insufficiently generalize to real-world practice. Observational studies are inclusive but often lack sufficient rigor. The workshop considered possible solutions, such as (1) statistical methods for demonstrating causality using observational data; (2) characteristics required of a registry supporting effectiveness research; (3) trial designs combining advantages of observational studies and RCTs; and (4) equipoise, an identified challenge for RCTs. In the future, advances in information technology potentially could lead to creation of a massive database where clinical data from all neu...
Low-income and-middle-income countries (LMICs) are increasing investment in research and development...
Low-income and middle-income countries (LMICs) face the greatest burden of neurotrauma. However, mos...
The overwhelming benefit demonstrated in the four recent randomized trials comparing intra-arterial ...
OBJECTIVE:To study and provide an update on the state of clinical research in neurology in the Unite...
ImportanceOne major advantage of developing large, federally funded networks for clinical research i...
International audienceA highlight of the congress was an interactive and inclusive discussion of the...
Background: Clinical research is necessary to evaluate neurosurgical interventions, yet clinical tri...
As a scientific field of study, neuroepidemiology encompasses more than just the descriptive study o...
Systematic reviews and meta-analyses constitute one of the central pillars of evidence-based medicin...
International audienceSystematic reviews and meta-analyses constitute one of the central pillars of ...
OBJECTIVE: Explore the value and potential of qualitative research to neurosurgery and provide insig...
Objective: The aim of this study was to investigate the effectiveness of interventions aimed at movi...
OBJECTIVE: The evidence-based medicine movement is gaining influence in many medical specialties. Al...
The historical development of neurology has hinged largely on keen observation and the ability of sk...
Object Technological innovation within health care may be defined as the introduction of a new techn...
Low-income and-middle-income countries (LMICs) are increasing investment in research and development...
Low-income and middle-income countries (LMICs) face the greatest burden of neurotrauma. However, mos...
The overwhelming benefit demonstrated in the four recent randomized trials comparing intra-arterial ...
OBJECTIVE:To study and provide an update on the state of clinical research in neurology in the Unite...
ImportanceOne major advantage of developing large, federally funded networks for clinical research i...
International audienceA highlight of the congress was an interactive and inclusive discussion of the...
Background: Clinical research is necessary to evaluate neurosurgical interventions, yet clinical tri...
As a scientific field of study, neuroepidemiology encompasses more than just the descriptive study o...
Systematic reviews and meta-analyses constitute one of the central pillars of evidence-based medicin...
International audienceSystematic reviews and meta-analyses constitute one of the central pillars of ...
OBJECTIVE: Explore the value and potential of qualitative research to neurosurgery and provide insig...
Objective: The aim of this study was to investigate the effectiveness of interventions aimed at movi...
OBJECTIVE: The evidence-based medicine movement is gaining influence in many medical specialties. Al...
The historical development of neurology has hinged largely on keen observation and the ability of sk...
Object Technological innovation within health care may be defined as the introduction of a new techn...
Low-income and-middle-income countries (LMICs) are increasing investment in research and development...
Low-income and middle-income countries (LMICs) face the greatest burden of neurotrauma. However, mos...
The overwhelming benefit demonstrated in the four recent randomized trials comparing intra-arterial ...