A clear correlation has been observed between the resonance Raman (RR) spectra of plaques in the aortic tunica intimal wall of a human corpse and three states of plaque evolution: fibrolipid plaques, calcified and ossified plaques, and vulnerable atherosclerotic plaques (VPs). These three states of atherosclerotic plaque lesions demonstrated unique RR molecular fingerprints from key molecules, rendering their spectra unique with respect to one another. The vibrational modes of lipids, cholesterol, carotenoids, tryptophan and heme proteins, the amide I, II, III bands, and methyl/methylene groups from the intrinsic atherosclerotic VPs in tissues were studied. The salient outcome of the investigation was demonstrating the correlation between R...
AbstractPurpose: Near-infrared Raman spectroscopy provides an important new means of analyzing the c...
Atherosclerosis, the major cause of cardiovascular diseases, has been a leading contributor to morbi...
Background: High resolution Magnetic Resonance Spectroscopy (MRS) in vitro was used to investigate t...
The chemical composition of vascular lesions, an important determinant of plaque progression and rup...
Vulnerable plaques, which are responsible for most acute ischemic events, are presently invisible to...
Accumulation of the lipid-protein complex ceroid is a characteristic of atherosclerotic plaque. The ...
Atherosclerosis is a vascular disease, initiated by damage to the endothelial cells, and characteriz...
Early detection and treatment of rupture-prone vulnerable atherosclerotic plaques is critical to red...
To accurately predict atherosclerotic plaque progression, a detailed phenotype of the lesion at the ...
To accurately predict atherosclerotic plaque progression, a detailed phenotype of the lesion at the ...
Raman spectroscopy can be applied to characterise the chemical composition of an atherosclerotic pla...
Background: Fluorescence lifetime imaging (FLIm) is a spectroscopic imaging technique able to charac...
This study presents the results of Raman spectroscopy applied to the classification of arterial tiss...
This work shows the application of vibrational spectroscopy supported by other complementary techniq...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer...
AbstractPurpose: Near-infrared Raman spectroscopy provides an important new means of analyzing the c...
Atherosclerosis, the major cause of cardiovascular diseases, has been a leading contributor to morbi...
Background: High resolution Magnetic Resonance Spectroscopy (MRS) in vitro was used to investigate t...
The chemical composition of vascular lesions, an important determinant of plaque progression and rup...
Vulnerable plaques, which are responsible for most acute ischemic events, are presently invisible to...
Accumulation of the lipid-protein complex ceroid is a characteristic of atherosclerotic plaque. The ...
Atherosclerosis is a vascular disease, initiated by damage to the endothelial cells, and characteriz...
Early detection and treatment of rupture-prone vulnerable atherosclerotic plaques is critical to red...
To accurately predict atherosclerotic plaque progression, a detailed phenotype of the lesion at the ...
To accurately predict atherosclerotic plaque progression, a detailed phenotype of the lesion at the ...
Raman spectroscopy can be applied to characterise the chemical composition of an atherosclerotic pla...
Background: Fluorescence lifetime imaging (FLIm) is a spectroscopic imaging technique able to charac...
This study presents the results of Raman spectroscopy applied to the classification of arterial tiss...
This work shows the application of vibrational spectroscopy supported by other complementary techniq...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer...
AbstractPurpose: Near-infrared Raman spectroscopy provides an important new means of analyzing the c...
Atherosclerosis, the major cause of cardiovascular diseases, has been a leading contributor to morbi...
Background: High resolution Magnetic Resonance Spectroscopy (MRS) in vitro was used to investigate t...