A multifunctional chemical neural probe fabrication process exploiting PDMS thin-film transfer to incorporate a microfluidic channel onto a silicon-based microelectrode array (MEA) platform, and enzyme microstamping to provide multi-analyte detection is described. The Si/PDMS hybrid chemtrode, modified with a nano-based on-probe IrOx reference electrode, was validated in brain phantoms and in rat brain
AbstractSilicon micromachined deep brain multielectrodes (up to 70mm) with monolithically integrated...
Dynamic chemical heterogeneity of the nervous system is essential to numerous physiological processe...
Brain function can be best studied by simultaneous measurements and modulation of the multifaceted s...
Implantable neural probes are one of the most important technologies for neuroscientists to detect a...
Abstract Intracortical microprobes allow the precise monitoring of electrical and chemical signaling...
Understanding interactions among neurons as they process information is important both for neural pr...
Neural microelectrodes are an important and essential component in neuroscience and neural prostheti...
The ability to monitor simultaneously the electrical activity of neurons and inter-neuronal chemical...
International audienceSimultaneous monitoring of glucose and lactate is an important challenge for u...
In neuroscience, understanding the complex functionality of the brain as an electrochemical system r...
Neural circuit processing is a poorly understood area of biology, but is critical to the development...
Microfabricated fluidic systems have emerged as a powerful approach for chemical analysis. Relativel...
Abstract The demand for multifunctional neural interfaces has grown due to the need to provide a bet...
The fine micro-architecture of neural tissue complicates efforts to create neural interface hardware...
[[abstract]]An implantable and dual functional needle-type microprobe (500 μm o.d.) composed of a mi...
AbstractSilicon micromachined deep brain multielectrodes (up to 70mm) with monolithically integrated...
Dynamic chemical heterogeneity of the nervous system is essential to numerous physiological processe...
Brain function can be best studied by simultaneous measurements and modulation of the multifaceted s...
Implantable neural probes are one of the most important technologies for neuroscientists to detect a...
Abstract Intracortical microprobes allow the precise monitoring of electrical and chemical signaling...
Understanding interactions among neurons as they process information is important both for neural pr...
Neural microelectrodes are an important and essential component in neuroscience and neural prostheti...
The ability to monitor simultaneously the electrical activity of neurons and inter-neuronal chemical...
International audienceSimultaneous monitoring of glucose and lactate is an important challenge for u...
In neuroscience, understanding the complex functionality of the brain as an electrochemical system r...
Neural circuit processing is a poorly understood area of biology, but is critical to the development...
Microfabricated fluidic systems have emerged as a powerful approach for chemical analysis. Relativel...
Abstract The demand for multifunctional neural interfaces has grown due to the need to provide a bet...
The fine micro-architecture of neural tissue complicates efforts to create neural interface hardware...
[[abstract]]An implantable and dual functional needle-type microprobe (500 μm o.d.) composed of a mi...
AbstractSilicon micromachined deep brain multielectrodes (up to 70mm) with monolithically integrated...
Dynamic chemical heterogeneity of the nervous system is essential to numerous physiological processe...
Brain function can be best studied by simultaneous measurements and modulation of the multifaceted s...