Add to ORKGStreptogramins are antibiotics produced by several species of Streptomyces bacteria that are used in both human and veterinary medicine. Group A streptogramins comprise 23-membered macrocyclic polyketide/nonribosomal peptide hybrids for which several innovative, fully synthetic routes have been developed. Herein we describe in detail our scalable routes to natural group A streptogramins and compare these routes to other reported syntheses
Bacteria in the genus Streptomyces and its close relatives are prolific producers of secondary metab...
The increasing resistance to antibiotics is becoming a major threat to public health. An increasing ...
Abstract Coelimycin P1 and argimycins P are two types of polyketide alkaloids produced by Streptomyc...
Streptogramin antibiotics are used clinically to treat multidrug-resistant bacterial infections, but...
Modular, fully synthetic routes to structurally complex natural products provide useful avenues to a...
Abstract: A number of new synthetic methods have been developed that are applicable to several types...
Natural products serve as chemical blueprints for most antibiotics in clinical use. The evolutionary...
Total synthesis of decapeptide antibiotics streptocidins A-D from Streptomyces sp. Tu 6071 was accom...
Actinomycete bacteria of the genus Streptomyces are major producers of bioactive compounds for the b...
The total synthesis of (±)-streptonigrin, a potent tetracyclic aminoquinoline-5,8-dione antitumor an...
The chemical modification of structurally complex fermentation products, a process known as semisynt...
The total synthesis of (±)-streptonigrin, a potent tetracyclic aminoquinoline-5,8-dione antitumor an...
Several recently accomplished total syntheses of antibiotic natural products were summarized in this...
AbstractActinomycetes are a rich source for the synthesis of medically and technically useful natura...
Streptomyces are producers of valuable secondary metabolites with unique scaffolds that perform a pl...
Bacteria in the genus Streptomyces and its close relatives are prolific producers of secondary metab...
The increasing resistance to antibiotics is becoming a major threat to public health. An increasing ...
Abstract Coelimycin P1 and argimycins P are two types of polyketide alkaloids produced by Streptomyc...
Streptogramin antibiotics are used clinically to treat multidrug-resistant bacterial infections, but...
Modular, fully synthetic routes to structurally complex natural products provide useful avenues to a...
Abstract: A number of new synthetic methods have been developed that are applicable to several types...
Natural products serve as chemical blueprints for most antibiotics in clinical use. The evolutionary...
Total synthesis of decapeptide antibiotics streptocidins A-D from Streptomyces sp. Tu 6071 was accom...
Actinomycete bacteria of the genus Streptomyces are major producers of bioactive compounds for the b...
The total synthesis of (±)-streptonigrin, a potent tetracyclic aminoquinoline-5,8-dione antitumor an...
The chemical modification of structurally complex fermentation products, a process known as semisynt...
The total synthesis of (±)-streptonigrin, a potent tetracyclic aminoquinoline-5,8-dione antitumor an...
Several recently accomplished total syntheses of antibiotic natural products were summarized in this...
AbstractActinomycetes are a rich source for the synthesis of medically and technically useful natura...
Streptomyces are producers of valuable secondary metabolites with unique scaffolds that perform a pl...
Bacteria in the genus Streptomyces and its close relatives are prolific producers of secondary metab...
The increasing resistance to antibiotics is becoming a major threat to public health. An increasing ...
Abstract Coelimycin P1 and argimycins P are two types of polyketide alkaloids produced by Streptomyc...