Telomerase is a ribonucleoprotein complex that counteracts the shortening of chromosome ends due to incomplete replication. Telomerase contains a catalytic core of telomerase reverse transcriptase (TERT) and telomerase RNA (TER). However, what defines TERT and separates it from other reverse transcriptases remains a subject of debate. A recent cryoelectron microscopy map of Tetrahymena telomerase revealed the structure of a previously uncharacterized TERT domain (TRAP) with unanticipated interactions with the telomerase essential N-terminal (TEN) domain and roles in telomerase activity. Both TEN and TRAP are absent in the putative Tribolium TERT that has been used as a model for telomerase for over a decade. To investigate the conservation ...
Telomerase is the ribonucleoprotein (RNP) reverse transcriptase responsible for synthesizing the 3' ...
Telomerase reverse transcriptase (TERT) and telomerase RNA (TER) function together to create a uniqu...
Telomerase is an enzyme that maintains telomeres, the protective structures at the ends of chromosom...
Telomerase is unique among the reverse transcriptases in containing a noncoding RNA (known as telome...
Telomerase is a DNA polymerase that extends the 3' ends of chromosomes by processively synthesizing ...
Telomerase is an RNP that synthesizes the 3' ends of linear chromosomes and is an important regulato...
During genome replication, telomerase adds repeats to the ends of chromosomes to balance the loss of...
The enzyme telomerase adds telomeric repeats to chromosome ends to balance the loss of telomeres dur...
Telomeres are dynamic nucleoprotein complexes that protect the fragile termini of chromosomes. With...
Telomerase maintains telomere length at the ends of linear chromosomes using an integral telomerase ...
Telomeres are specialized protein-DNA structures that protect the ends of linear chromosomes, and th...
Functional human telomerase complexes are minimally composed of the human telomerase RNA (hTR) and a...
Telomerase adds telomeric repeats to chromosome ends using an internal RNA template and specialized ...
Telomerase is an RNA-protein complex comprising telomerase reverse transcriptase, a non-coding telom...
Telomerase is a ribonucleoprotein reverse transcriptase that extends the ends of chromosomes. The tw...
Telomerase is the ribonucleoprotein (RNP) reverse transcriptase responsible for synthesizing the 3' ...
Telomerase reverse transcriptase (TERT) and telomerase RNA (TER) function together to create a uniqu...
Telomerase is an enzyme that maintains telomeres, the protective structures at the ends of chromosom...
Telomerase is unique among the reverse transcriptases in containing a noncoding RNA (known as telome...
Telomerase is a DNA polymerase that extends the 3' ends of chromosomes by processively synthesizing ...
Telomerase is an RNP that synthesizes the 3' ends of linear chromosomes and is an important regulato...
During genome replication, telomerase adds repeats to the ends of chromosomes to balance the loss of...
The enzyme telomerase adds telomeric repeats to chromosome ends to balance the loss of telomeres dur...
Telomeres are dynamic nucleoprotein complexes that protect the fragile termini of chromosomes. With...
Telomerase maintains telomere length at the ends of linear chromosomes using an integral telomerase ...
Telomeres are specialized protein-DNA structures that protect the ends of linear chromosomes, and th...
Functional human telomerase complexes are minimally composed of the human telomerase RNA (hTR) and a...
Telomerase adds telomeric repeats to chromosome ends using an internal RNA template and specialized ...
Telomerase is an RNA-protein complex comprising telomerase reverse transcriptase, a non-coding telom...
Telomerase is a ribonucleoprotein reverse transcriptase that extends the ends of chromosomes. The tw...
Telomerase is the ribonucleoprotein (RNP) reverse transcriptase responsible for synthesizing the 3' ...
Telomerase reverse transcriptase (TERT) and telomerase RNA (TER) function together to create a uniqu...
Telomerase is an enzyme that maintains telomeres, the protective structures at the ends of chromosom...