Add to ORKGEarly work stressed the differing involvement of the central amygdala (CeA) and bed nucleus of the stria terminalis (BNST) in the genesis of fear versus anxiety, respectively. In 2009, Walker, Miles, and Davis proposed a model of amygdala-BNST interactions to explain these functional differences. This model became extremely influential and now guides a new wave of studies on the role of BNST in humans. Here, we consider evidence for and against this model, in the process highlighting central principles of BNST organization. This analysis leads us to conclude that BNST's influence is not limited to the generation of anxiety-like responses to diffuse threats, but that it also shapes the impact of discrete threatening stimuli. It is likely tha...
Sustained anticipatory anxiety is central to Generalized Anxiety Disorder (GAD). During anticipatory...
When extreme, anxiety-a state of distress and arousal prototypically evoked by uncertain danger-can ...
While learning to fear stimuli that predict danger promotes survival, the inability to inhibit fear ...
It is widely thought that phasic and sustained responses to threat reflect dissociable circuits cent...
It is widely thought that phasic and sustained responses to threat reflect dissociable circuits cent...
It is widely thought that phasic and sustained responses to threat reflect dissociable circuits cent...
Anxiety disorders impose a staggering burden on public health, underscoring the need to develop a de...
The anterior part of the bed nucleus of the stria terminalis (BNST-A) has emerged as a critical stru...
The bed nucleus of the stria terminalis (BNST) is a poorly understood brain structure. Most prior be...
The amygdala and, more recently, also the bed nucleus of the stria terminalis, have been widely impl...
The ability to adaptively regulate responses to the proximity of potential danger is critical to sur...
The central nucleus of the amygdala (CeA) and the lateral division of the bed nucleus of the stria t...
A growing body of research supports a prominent role for the bed nucleus of the stria terminalis (BS...
Based on anatomical similarities, it has been argued that the amygdala, bed nucleus of the stria ter...
This thesis examined the functional organization of the bed nucleus of the stria terminalis (BNST), ...
Sustained anticipatory anxiety is central to Generalized Anxiety Disorder (GAD). During anticipatory...
When extreme, anxiety-a state of distress and arousal prototypically evoked by uncertain danger-can ...
While learning to fear stimuli that predict danger promotes survival, the inability to inhibit fear ...
It is widely thought that phasic and sustained responses to threat reflect dissociable circuits cent...
It is widely thought that phasic and sustained responses to threat reflect dissociable circuits cent...
It is widely thought that phasic and sustained responses to threat reflect dissociable circuits cent...
Anxiety disorders impose a staggering burden on public health, underscoring the need to develop a de...
The anterior part of the bed nucleus of the stria terminalis (BNST-A) has emerged as a critical stru...
The bed nucleus of the stria terminalis (BNST) is a poorly understood brain structure. Most prior be...
The amygdala and, more recently, also the bed nucleus of the stria terminalis, have been widely impl...
The ability to adaptively regulate responses to the proximity of potential danger is critical to sur...
The central nucleus of the amygdala (CeA) and the lateral division of the bed nucleus of the stria t...
A growing body of research supports a prominent role for the bed nucleus of the stria terminalis (BS...
Based on anatomical similarities, it has been argued that the amygdala, bed nucleus of the stria ter...
This thesis examined the functional organization of the bed nucleus of the stria terminalis (BNST), ...
Sustained anticipatory anxiety is central to Generalized Anxiety Disorder (GAD). During anticipatory...
When extreme, anxiety-a state of distress and arousal prototypically evoked by uncertain danger-can ...
While learning to fear stimuli that predict danger promotes survival, the inability to inhibit fear ...