414. CAR Spacers Including NGFR Domains Allow Efficient T-Cell Tracking and Mediate Superior Antitumor Effects

Monica Casucci
Laura Falcone
Barbara Camisa
Chiara Bonini
Attilio Bondanza

Open PDF

Open link

Publication date

May 2015

DOI

10.1016/s1525-0016(16)34023-0

Language

English

Abstract

In conclusion, we demonstrated that the incorporation of the LNGFR marker gene directly in the CAR sequence allows for a single molecule to work as a therapeutic and as a selection/tracking gene and shows an increased efficacy/safety profile compared to the IgG1-CH2CH3 spacer

Extracted data

We use cookies to provide a better user experience.

Data Protection

414. CAR Spacers Including NGFR Domains Allow Efficient T-Cell Tracking and Mediate Superior Antitumor Effects

Abstract

Extracted data

414. CAR Spacers Including NGFR Domains Allow Efficient T-Cell Tracking and Mediate Superior Antitumor Effects

Abstract

Extracted data

Related items

Related items