In this paper, we examine a recently introduced type of effective reduction which applies solely to problems of equivalence or isomorphism: the "kernel reduction". Specifically, we examine reductions among languages in the complexity class consisting of all languages induced by equivalence relations for which membership can be decided by a non-deterministic polynomial time Turing machine. This class is called "NPEq"; the definitions for PEq and coNPEq are analogous. We prove a general theorem which provides a problem which is hard under polynomial time kernel reductions for several classes of equivalence relations, including (Sigma_k)PEq and PSPACEEq. In fact, such a problem is complete for PSPACEEq under polynomial time kernel reduction...