Reducing Dscam1 diversity affects axonal branching in MS neurons.

Related to Fig 5. (A) Schematic of the pSc neuron. Different colors of branch segments were assigned for scoring. Representative images of WT and Dscam1 mutant flies. Scale bar, 50 μm. (B) Quantitative analysis of the total branch number of pSc neurons in WT and Dscam1 mutants. Numbers in parentheses represent the number of pSc neurons observed in each genotype. ns, not significant; *P P P t test, two-tailed). (C) The average branch number of pSc neurons positively correlated with the number of variable exon 4, exon 6, and exon 9. (D) Comparison of phenotype–diversity correlates among variable exon 4, exon 6, and exon 9 clusters were shown. Data used to generate graphs can be found in S1 Data. Dscam1, Down syndrome cell adhesion molecule 1; MS, mechanosensory; WT, wild type. (TIF)