In his Problema XXX, I, Aristotle poses the question: ”Why is it that all those who have become eminent in philosophy or politics or poetry or the arts clearly are melancholics?” This article is concerned with how, during the French Renaissance, poets such as Pierre de Ronsard (1524–85) and Joachim du Bellay (1522– 60) began, in the footsteps of ”Nostradamus”, Michel de Nostredame (1503–66), to investigate this ”problem” in their search for genius, heroism, and creativity. Both poets fitted into the humanist poetic tradition inspired by the Neo-Platonism of Marsilio Ficino (1433–1499), who was the climax of a long line of modern exegetes of the Aristotelian passage. According to Ficino, the idea of melancholy touched on advanced and c...