The first step in identifying proteins from mass spectrometry based shotgun proteomics data is to infer peptides from tandem mass spectra, a task generally achieved using database search engines. In this chapter, the basic principles of database search engines are introduced with a focus on open source software, and the use of database search engines is demonstrated using the freely available SearchGUI interface. This chapter also discusses how to tackle general issues related to sequence database searching and shows how to minimize their impact.The first step in identifying proteins from mass spectrometry based shotgun proteomics data is to infer peptides from tandem mass spectra, a task generally achieved using database search engines. In...
In mass spectrometry-based proteomics, most conventional search engines match spectral data to seque...
AbstractThe subject of this tutorial is protein identification and characterisation by database sear...
Spectral library searching is a new approach in proteomic data analysis that promises to address som...
The first step in identifying proteins from mass spectrometry based shotgun proteomics data is to in...
The first step in identifying proteins from mass spectrometry based shotgun proteomics data is to in...
Sequence database search engines are bioinformatics algorithms that identify peptides from tandem ma...
Sequence database search engines are bioinformatics algorithms that identify peptides from tandem ma...
Sequence database search engines are bioinformatics algorithms that identify peptides from tandem ma...
The bottom-up proteomics approach (also known as the shotgun approach), based on the digestion of pr...
Shotgun proteomics is a widely known technique for identification of protein and peptide sequences f...
Shotgun proteomics is a widely known technique for identification of protein and peptide sequences f...
Mass-spectrometry-based proteomics has become the standard approach for identifying and quantifying ...
The bottom-up proteomics approach (also known as the shotgun approach), based on the digestion of pr...
The bottom-up proteomics approach (also known as the shotgun approach), based on the digestion of pr...
In mass spectrometry-based proteomics, most conventional search engines match spectral data to seque...
In mass spectrometry-based proteomics, most conventional search engines match spectral data to seque...
AbstractThe subject of this tutorial is protein identification and characterisation by database sear...
Spectral library searching is a new approach in proteomic data analysis that promises to address som...
The first step in identifying proteins from mass spectrometry based shotgun proteomics data is to in...
The first step in identifying proteins from mass spectrometry based shotgun proteomics data is to in...
Sequence database search engines are bioinformatics algorithms that identify peptides from tandem ma...
Sequence database search engines are bioinformatics algorithms that identify peptides from tandem ma...
Sequence database search engines are bioinformatics algorithms that identify peptides from tandem ma...
The bottom-up proteomics approach (also known as the shotgun approach), based on the digestion of pr...
Shotgun proteomics is a widely known technique for identification of protein and peptide sequences f...
Shotgun proteomics is a widely known technique for identification of protein and peptide sequences f...
Mass-spectrometry-based proteomics has become the standard approach for identifying and quantifying ...
The bottom-up proteomics approach (also known as the shotgun approach), based on the digestion of pr...
The bottom-up proteomics approach (also known as the shotgun approach), based on the digestion of pr...
In mass spectrometry-based proteomics, most conventional search engines match spectral data to seque...
In mass spectrometry-based proteomics, most conventional search engines match spectral data to seque...
AbstractThe subject of this tutorial is protein identification and characterisation by database sear...
Spectral library searching is a new approach in proteomic data analysis that promises to address som...