alpha-GalCer (also known as KRN7000) is an immunomodulatory glycolipid that is known to potently activate invariant natural killer T (NKT) cells upon CD1d-mediated stimulation. Because Th1 and Th2 cytokines, which are released after alpha-GalCer presentation, antagonize each other's effects, a-GalCer analogues-that induce a biased Th1/Th2 response are highly awaited. In this context, we report the synthesis and in vitro evaluation of alpha-Gal-D-Xylo-Cer and two alpha-Gal-L-lyxo-Cer analogues, one with the natural acyl chain, the other with a truncated chain.alpha-GalCer (also known as KRN7000) is an immunomodulatory glycolipid that is known to potently activate invariant natural killer T (NKT) cells upon CD1d-mediated stimulation. Because ...
NKT cells, a unique subset of T cells that recognizes glycolipid antigens presented by CD1d molecule...
The glycolipid α-galactosyl ceramide, α-GalCer, has been shown to stimulate the proliferation of mur...
International audienceNatural killer T (NKT) cells are a distinct subset of mature lymphocytes endow...
alpha-GalCer (also known as KRN7000) is an immunomodulatory glycolipid that is known to potently act...
?-GalCer (also known as KRN7000) is an immunomodulatory glycolipid that is known to potently activat...
?-Galactosyl ceramide (?-GalCer, also known as KRN 7000) is known as the prototypical antigen for in...
Alpha-Galactosylceramides are known to activate invariant natural killer (iNK) T cells which are a s...
Natural Killer T (NKT) cells are a subset of mature T lymphocytes which have been shown to play a ma...
Natural killer T (NKT) cells are a subset of T cells that recognizes and is activated by glycolipid ...
Stimulation of iNKT cells by α-galactosyl ceramide (α-GalCer), also known as KRN7000, and its trunca...
Invariant natural killer T-cells (iNKT) are a glycolipid-responsive subset of T-lymphocytes that ful...
Activation of CD1d-restricted invariant NKT (iNKT) cells with the glycolipid α-galactosylceramide (α...
Natural killer T (NKT) cell is a distinct population of T lymphocytes that can rapidly release massi...
AbstractStimulation of iNKT cells by α-galactosyl ceramide (α-GalCer), also known as KRN7000, and it...
Stimulation of iNKT cells by α-galactosyl ceramide (α-GalCer), also known as KRN7000, and its trunca...
NKT cells, a unique subset of T cells that recognizes glycolipid antigens presented by CD1d molecule...
The glycolipid α-galactosyl ceramide, α-GalCer, has been shown to stimulate the proliferation of mur...
International audienceNatural killer T (NKT) cells are a distinct subset of mature lymphocytes endow...
alpha-GalCer (also known as KRN7000) is an immunomodulatory glycolipid that is known to potently act...
?-GalCer (also known as KRN7000) is an immunomodulatory glycolipid that is known to potently activat...
?-Galactosyl ceramide (?-GalCer, also known as KRN 7000) is known as the prototypical antigen for in...
Alpha-Galactosylceramides are known to activate invariant natural killer (iNK) T cells which are a s...
Natural Killer T (NKT) cells are a subset of mature T lymphocytes which have been shown to play a ma...
Natural killer T (NKT) cells are a subset of T cells that recognizes and is activated by glycolipid ...
Stimulation of iNKT cells by α-galactosyl ceramide (α-GalCer), also known as KRN7000, and its trunca...
Invariant natural killer T-cells (iNKT) are a glycolipid-responsive subset of T-lymphocytes that ful...
Activation of CD1d-restricted invariant NKT (iNKT) cells with the glycolipid α-galactosylceramide (α...
Natural killer T (NKT) cell is a distinct population of T lymphocytes that can rapidly release massi...
AbstractStimulation of iNKT cells by α-galactosyl ceramide (α-GalCer), also known as KRN7000, and it...
Stimulation of iNKT cells by α-galactosyl ceramide (α-GalCer), also known as KRN7000, and its trunca...
NKT cells, a unique subset of T cells that recognizes glycolipid antigens presented by CD1d molecule...
The glycolipid α-galactosyl ceramide, α-GalCer, has been shown to stimulate the proliferation of mur...
International audienceNatural killer T (NKT) cells are a distinct subset of mature lymphocytes endow...