Vorrichtung und Verfahren zur Detektion von in fluessigen Proben enthaltenen Analytmolekuelen

DE 102008062620 A1 UPAB: 20100729 NOVELTY - The device has a measuring channel (2) at which two openings (11, 12) are provided for supply and discharge of a fluid sample. A flat metallic thick- or thin layer is arranged as an electrode (1) at a channel wall between the openings, and electrically conductive strip-shaped thin layers are arranged as a set of electrodes opposite to the electrode. An electric voltage potential is maintained at the set of electrodes for forming an inhomogeneous electric field. Ligands above the electrode contact the sample, are in communication with the channel and are immobilized on a measuring surface. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for a method for detecting analyte molecules in a fluid sample. USE - Device i.e. quartz microbalance (claimed), for detecting analyte molecules e.g. protein and DNA, in a fluid sample. ADVANTAGE - The device is designed such that biding rate and/or selectivity of binding of the analyte molecules in the fluid sample to the immobilized ligands are increased and/or improved, and shortening time required for binding